A Supportive Role of Mesenchymal Stem Cells on Insulin-Producing Langerhans Islets with a Specific Emphasis on The Secretome

RV Sionov, R Ahdut-HaCohen - Biomedicines, 2023 - mdpi.com
Type 1 Diabetes (T1D) is a chronic autoimmune disease characterized by a gradual
destruction of insulin-producing β-cells in the endocrine pancreas due to innate and specific …

Bone morphogenetic protein signalling in pulmonary arterial hypertension: revisiting the BMPRII connection

W Li, K Quigley - Biochemical Society Transactions, 2024 - portlandpress.com
Pulmonary arterial hypertension (PAH) is a rare and life-threatening vascular disorder,
characterised by abnormal remodelling of the pulmonary vessels and elevated pulmonary …

Characterization of erythroferrone oligomerization and its impact on BMP antagonism

JF Mast, EAE Leach, TB Thompson - Journal of Biological Chemistry, 2024 - ASBMB
Hepcidin, a peptide hormone that negatively regulates iron metabolism, is expressed by
bone morphogenetic protein (BMP) signaling. Erythroferrone (ERFE) is an extracellular …