The current management of thalassemia includes regular transfusion programs and
chelation therapy. It is important that physicians be aware that endocrine abnormalities …

Patients with multi-transfused Thalassaemia Major (TM) may develop severe endocrine
complications. Iron overload due to multiple transfusions is the main cause of such …

Advances in treatment of thalassemia have led to the aging of thalassemic patients, and
consequently concern about successful reproductive outcome is augmented. Although …

Background: Thalassemia major is an inherited hemoglobin disorder characterized by
chronic anemia and iron overload due to transfusion therapy and gastrointestinal …

Endocrine dysfunction in Thalassaemia major (TM) is a common and disturbing
complication, which requires prompt recognition and treatment. The contribution of the …

Background: The clinical severity in thalassaemia major (TM) depends on the underlying
mutations of the β‐globin gene and the degree of iron overload. Objective: The aim of the …

Hemoglobinopathies are autosomal recessive disorders that occur when genetic mutations
negatively impact the function of hemoglobin. Common hemoglobinopathies that are …

Aims. The current study had three aims:(i) to examine disease knowledge in both
thalassemia major patients and their mothers;(ii) to understand the relationships between …

In the not so distant past, pregnancy for women with transfusion-dependent thalassemia
(TDT) was considered very high risk and often not recommended. As management of these …

Iron plays a critical role in a mammal's physiological processes. However, iron tissue
deposits have been shown to act as endocrine disrupters. Studies that evaluate the effect of …