Quinone methides (QMs) are highly reactive compounds that have been defined as “elusive”
intermediates, or even as a “synthetic enigma” in organic chemistry. Indeed, there were just …

A remaining challenge in the synthetic chemistry field is formation of all-carbon quaternary
centers, a feature found in many natural products, particularly in spirocycle systems. 1 …

Catalysis by small molecules (≤ 1000 Da, 10− 9 m) that are capable of binding and
activating substrates through attractive, noncovalent interactions has emerged as an …

The cation− π interaction is an attractive noncovalent interaction between a cation and a π
system. Due to the stronger interaction energy than those of the other π interactions, such as …

A concise synthesis of pyrazolo [1, 5‐a] indole derivatives by copper‐catalyzed aerobic
oxygenation and cyclization of indoles with oxime acetates is described. This protocol …

Oxidation of indoles is a fundamental organic transformation to deliver a variety of
synthetically and pharmaceutically valuable nitrogen-containing compounds. Prior methods …

Catalytic asymmetric dearomatization of heteroaromatic compounds has received
considerable attention in the last few years, since it allows for a fast expansion of the …

Chemical composition of DNA-encoded libraries, past present and future - Organic &
Biomolecular Chemistry (RSC Publishing) DOI:10.1039/C9OB00581A Royal Society of …

Direct enantioselective synthesis of chiral aza-quaternary carbon indolenines through the
dearomative electrophilic hydrazination of 2, 3-disubstituted indoles has been achieved …

For almost 20 years, thioureas have been experiencing a renaissance of interest with the
emerged development of asymmetric organocatalysts. Due to their relatively high acidity and …