Collective cell migration in development

L Schumacher - Cell migrations: causes and functions, 2019 - Springer
Collective cell migration is a key process in developmental biology, facilitating the bulk
movement of cells in the morphogenesis of animal tissues. Predictive understanding in this …

Collective behavior and nongenetic inheritance allow bacterial populations to adapt to changing environments

HH Mattingly, T Emonet - Proceedings of the National …, 2022 - National Acad Sciences
Collective behaviors require coordination among a group of individuals. As a result,
individuals that are too phenotypically different from the rest of the group can be left out …

Picking winners in cell-cell collisions: Wetting, speed, and contact

P Zadeh, BA Camley - Physical Review E, 2022 - APS
Groups of eukaryotic cells can coordinate their crawling motion to follow cues more
effectively, stay together, or invade new areas. This collective cell migration depends on cell …

Physical limits on galvanotaxis

I Nwogbaga, AH Kim, BA Camley - Physical Review E, 2023 - APS
Eukaryotic cells can polarize and migrate in response to electric fields via “galvanotaxis,”
which aids wound healing. Experimental evidence suggests cells sense electric fields via …

Photoactivatable substrates show diverse phenotypes of leader cells in collective migration when moving along different extracellular matrix proteins

SA Abdellatef, F Bard, J Nakanishi - Biomaterials Science, 2024 - pubs.rsc.org
In cancer metastasis, collectively migrating clusters are discriminated into leader and
follower cells that move through extracellular matrices (ECMs) with different characteristics …

Collective gradient sensing with limited positional information

EP Ipiña, BA Camley - Physical Review E, 2022 - APS
Eukaryotic cells sense chemical gradients to decide where and when to move. Clusters of
cells can sense gradients more accurately than individual cells by integrating measurements …

Chemotaxis in uncertain environments: Hedging bets with multiple receptor types

A Hopkins, BA Camley - Physical Review Research, 2020 - APS
Eukaryotic cells are able to sense chemical gradients in a wide range of environments. We
show that, if a cell is exposed to a highly variable environment, it may gain chemotactic …

New mathematical modelling tools for co-culture experiments: when do we need to explicitly account for signalling molecules?

W Jin, H Wang, X Liang, MS Roberts, MJ Simpson - bioRxiv, 2020 - biorxiv.org
Mathematical models are often applied to describe cell migration regulated by diffusible
signalling molecules. A typical feature of these models is that the spatial and temporal …