Quantifying brain microstructure with diffusion MRI: Theory and parameter estimation

DS Novikov, E Fieremans, SN Jespersen… - NMR in …, 2019 - Wiley Online Library
We review, systematize and discuss models of diffusion in neuronal tissue, by putting them
into an overarching physical context of coarse‐graining over an increasing diffusion length …

Imaging brain microstructure with diffusion MRI: practicality and applications

DC Alexander, TB Dyrby, M Nilsson… - NMR in …, 2019 - Wiley Online Library
This article gives an overview of microstructure imaging of the brain with diffusion MRI and
reviews the state of the art. The microstructure‐imaging paradigm aims to estimate and map …

[HTML][HTML] SANDI: a compartment-based model for non-invasive apparent soma and neurite imaging by diffusion MRI

M Palombo, A Ianus, M Guerreri, D Nunes… - Neuroimage, 2020 - Elsevier
This work introduces a compartment-based model for apparent cell body (namely soma) and
neurite density imaging (SANDI) using non-invasive diffusion-weighted MRI (DW-MRI). The …

[HTML][HTML] Connectome 2.0: Developing the next-generation ultra-high gradient strength human MRI scanner for bridging studies of the micro-, meso-and macro …

SY Huang, T Witzel, B Keil, A Scholz, M Davids, P Dietz… - NeuroImage, 2021 - Elsevier
The first phase of the Human Connectome Project pioneered advances in MRI technology
for mapping the macroscopic structural connections of the living human brain through the …

[HTML][HTML] Challenges for biophysical modeling of microstructure

IO Jelescu, M Palombo, F Bagnato… - Journal of Neuroscience …, 2020 - Elsevier
The biophysical modeling efforts in diffusion MRI have grown considerably over the past 25
years. In this review, we dwell on the various challenges along the journey of bringing a …

Combined diffusion‐relaxometry microstructure imaging: Current status and future prospects

PJ Slator, M Palombo, KL Miller… - Magnetic resonance …, 2021 - Wiley Online Library
Microstructure imaging seeks to noninvasively measure and map microscopic tissue
features by pairing mathematical modeling with tailored MRI protocols. This article reviews …

Microstructural imaging of the human brain with a 'super-scanner': 10 key advantages of ultra-strong gradients for diffusion MRI

DK Jones, DC Alexander, R Bowtell, M Cercignani… - NeuroImage, 2018 - Elsevier
The key component of a microstructural diffusion MRI 'super-scanner'is a dedicated high-
strength gradient system that enables stronger diffusion weightings per unit time compared …

On the scaling behavior of water diffusion in human brain white matter

J Veraart, E Fieremans, DS Novikov - NeuroImage, 2019 - Elsevier
Abstract Development of therapies for neurological disorders depends on our ability to non-
invasively diagnose and monitor the progression of underlying pathologies at the cellular …

[HTML][HTML] Diffusion-weighted imaging: recent advances and applications

E Martinez-Heras, F Grussu, F Prados, E Solana… - Seminars in Ultrasound …, 2021 - Elsevier
Quantitative diffusion imaging techniques enable the characterization of tissue
microstructural properties of the human brain “in vivo”, and are widely used in neuroscientific …

[HTML][HTML] The functional characterization of callosal connections

GM Innocenti, K Schmidt, C Milleret, M Fabri… - Progress in …, 2022 - Elsevier
The brain operates through the synaptic interaction of distant neurons within flexible, often
heterogeneous, distributed systems. Histological studies have detailed the connections …