Specific RNA sequences modified by a methylated adenosine, N 6-methyladenosine (m 6
A), contribute to the post-transcriptional regulation of gene expression. The quantity of m 6 A …

RNA methylation is a critical mechanism for regulating the transcription and translation of
specific sequences or for eliminating unnecessary sequences during RNA maturation …

RNA modifications are dynamic and reversible chemical modifications on substrate RNA
that are regulated by specific modifying enzymes. They play important roles in the regulation …

Numerous strategies are employed by cancer cells to control gene expression and facilitate
tumorigenesis. In the study of epitranscriptomics, a diverse set of modifications to RNA …

Highlights•RNA-binding proteins (RBPs) are essential for tumorigenesis, immune evasion,
invasion, migration and metastasis, hence promising drug targets in cancer therapy.•Small …

Various chemical modifications of all RNA transcripts, or epitranscriptomics, have emerged
as crucial regulators of RNA metabolism, attracting significant interest from both basic and …

Chemical modifications are a specific and efficient way to regulate the function of biological
macromolecules. Among them, RNA molecules exhibit a variety of modifications that play …

In recent years, advances in biomedicine have revealed an important role for post-
transcriptional mechanisms of gene expression regulation in pathologic conditions. In …

To date, over 150 chemical modifications to the four canonical RNA bases have been
discovered, known collectively as the epitranscriptome. Many of these modifications have …

YTHDF proteins are main cytoplasmic 'reader'proteins of RNA N 6-methyladenosine (m 6 A)
methylation in mammals. They are largely responsible for m 6 A-mediated regulation in the …