Endogenous opiates and behavior: 2005
RJ Bodnar, GE Klein - Peptides, 2006 - Elsevier
This paper is the 28th consecutive installment of the annual review of research concerning
the endogenous opioid system, now spanning over a quarter-century of research. It …
the endogenous opioid system, now spanning over a quarter-century of research. It …
Non-nociceptive roles of opioids in the CNS: opioids' effects on neurogenesis, learning, memory and affect
Mortality due to opioid use has grown to the point where, for the first time in history, opioid-
related deaths exceed those caused by car accidents in many states in the United States …
related deaths exceed those caused by car accidents in many states in the United States …
Prescription opioid analgesics rapidly change the human brain
Chronic opioid exposure is known to produce neuroplastic changes in animals; however, it
is not known if opioids used over short periods of time and at analgesic dosages can …
is not known if opioids used over short periods of time and at analgesic dosages can …
BDNF is a negative modulator of morphine action
Brain-derived neurotrophic factor (BDNF) is a key positive regulator of neural plasticity,
promoting, for example, the actions of stimulant drugs of abuse such as cocaine. We …
promoting, for example, the actions of stimulant drugs of abuse such as cocaine. We …
[HTML][HTML] Role for mTOR signaling and neuronal activity in morphine-induced adaptations in ventral tegmental area dopamine neurons
While the abuse of opiate drugs continues to rise, the neuroadaptations that occur with long-
term drug exposure remain poorly understood. We describe here a series of chronic …
term drug exposure remain poorly understood. We describe here a series of chronic …
Opiate-induced molecular and cellular plasticity of ventral tegmental area and locus coeruleus catecholamine neurons
MS Mazei-Robison, EJ Nestler - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
The study of neuronal adaptations induced by opiate drugs is particularly relevant today
given their widespread prescription and nonprescription use. Although much is known about …
given their widespread prescription and nonprescription use. Although much is known about …
Adult hippocampal neurogenesis in the pathogenesis of addiction and dual diagnosis disorders
RA Chambers - Drug and alcohol dependence, 2013 - Elsevier
BACKGROUND: As knowledge deepens about how new neurons are born, differentiate,
and wire into the adult mammalian brain, growing evidence depicts hippocampal …
and wire into the adult mammalian brain, growing evidence depicts hippocampal …
Chronic pain and adult hippocampal neurogenesis: translational implications from preclinical studies
M Grilli - Journal of pain research, 2017 - Taylor & Francis
Adult hippocampal neurogenesis (ahNG) occurs in the human brain. Adult generated
neurons have been proposed to functionally contribute to relevant hippocampal functions …
neurons have been proposed to functionally contribute to relevant hippocampal functions …
Endogenous morphine and its metabolites in mammals: history, synthesis, localization and perspectives
A Laux-Biehlmann, J Mouheiche, J Veriepe, Y Goumon - Neuroscience, 2013 - Elsevier
Morphine derived from Papaver somniferum is commonly used as an analgesic compound
for pain relief. It is now accepted that endogenous morphine, structurally identical to vegetal …
for pain relief. It is now accepted that endogenous morphine, structurally identical to vegetal …
Effect of opioid on adult hippocampal neurogenesis
During the past decade, the study of the mechanisms and functional implications of adult
neurogenesis has significantly progressed. Many studies focus on the factors that regulate …
neurogenesis has significantly progressed. Many studies focus on the factors that regulate …