Prostate cancer (PCa) is the most common worldwide diagnosed malignancy in male
population. The diagnosis, the identification of aggressive disease, and the post-treatment …

Tumour dormancy and recurrent metastatic cancer remain the greatest clinical challenge for
cancer patients. Dormant tumour cells can evade treatment and detection, while retaining …

The power of cryo-electron tomography (cryoET) lies in its capability to characterize
macromolecules in their cellular context. Structure determination by cryoET, however, is time …

Context Intermediate-risk prostate cancer consists of a highly heterogeneous group of
patients. Owing to this heterogeneity and variable prognoses, it is challenging to provide …

Predicting and treating recurrence in intermediate-risk prostate cancer patients remains a
challenge despite having identified genomic instability and hypoxia [,] as risk factors. This …

Background Recent retrospective data suggest that neoadjuvant androgen deprivation
therapy can improve the prognosis of high-risk prostate cancer (PCa) patients. Novel …

The possible role of the naturally occurring deuterium in the regulation of cell division was
first described in the 1990s. To investigate the mechanism of influence of deuterium (D) on …

Long-term follow-up care among prostate cancer patients is important as biochemical
recurrence can occur many years after diagnosis, with 20%–30% of men experiencing …

Objective Although surveillance after radical prostatectomy routinely includes repeated
prostate specific antigen (PSA)-testing for many years, biochemical recurrence often occurs …

The pathological grade of prostate cancer is the strongest predictor of recurrence. It is
unclear whether the better predictor is the composite of all carcinomas within the prostate, or …