Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …

Overweight and obesity are now considered a worldwide pandemic and a growing public
health problem with severe economic and social consequences. Adipose tissue is an organ …

Obesity is an ever-increasing phenomenon, with 42% of Americans being considered obese
(BMI≥ 30) and 9.2% being considered morbidly obese (BMI≥ 40) as of 2016. With obesity …

Branched-chain fatty acids (BCFA) are a group of lipids that are widely present in various
organisms; they take part in numerous biochemical processes and affect multiple signaling …

Acute inflammation is a critical host defense response during viral infection. When
dysregulated, inflammation drives immunopathology and tissue damage. Excessive …

Recently, we have demonstrated a decreased level of iso-branched-chain fatty acids (iso-
BCFAs) in patients with excessive weight. However, it is still unclear whether BCFAs may …

Metabolic syndrome (MetS) associated with obesity is a pathological condition increasing
worldwide. Recent studies have demonstrated that the neutrophil to lymphocyte ratio (NLR) …

IL-6 was found to be overexpressed in the adipose tissue of obese individuals, which may
cause insulin resistance. However, the regulation of IL-6 in adipocytes in obesity setting …

Obesity induces multifactorial effects such as dyslipidemia, insulin resistance, and arterial
hypertension that influence the progression of many diseases. Obesity is associated with an …

Obesity with its associated complications represents a social, economic and health problem
of utmost importance worldwide. Specifically, obese patients carry a significantly higher risk …