Background: Exercise leads to a robust inflammatory response mainly characterized by the
mobilization of leukocytes and an increase in circulating inflammatory mediators produced …

An ever-growing volume of peer-reviewed publications speaks to the recent and rapid
growth in both scope and understanding of exercise immunology. Indeed, more than 95% of …

Acute physical activity leads to several changes in metabolic, cardiovascular, and immune
pathways. Although studies have examined selected changes in these pathways, the system …

Chronic, systemic inflammation is an independent risk factor for several major clinical
diseases. In obesity, circulating levels of inflammatory markers are elevated, possibly due to …

This article emphasizes significant recent advances regarding heat stress and its impact on
exercise performance, adaptations, fluid electrolyte imbalances, and pathophysiology …

In our genome-wide survey of gene expression in human peripheral blood cells using both
an expressed sequence tag (EST) and a microarray hybridization approach, we identified …

The thioredoxin (Trx) system comprises Trx, truncated Trx (Trx-80), Trx reductase, and
NADPH, besides a natural Trx inhibitor, the thioredoxin-interacting protein (TXNIP). This …

Protein quality control (proteostasis) depends on constant protein degradation and
resynthesis, and is essential for proper homeostasis in systems from single cells to whole …

Epidemiological and prospective studies indicate that comprehensive lifestyle changes may
modify the progression of prostate cancer. However, the molecular mechanisms by which …

Advances in laboratory sciences offer much in the challenge to unravel the complex etiology
of cancer and to therefore provide an evidence‐base for prevention. One area where …