Candida albicans is a commensal yeast fungus of the human oral, gastrointestinal, and
genital mucosal surfaces, and skin. Antibiotic-induced dysbiosis, iatrogenic …

Lactobacilli are among the most studied bacteria in the microbiome of the orodigestive and
genitourinary tracts. As probiotics, lactobacilli may provide various benefits to the host …

The human pathogenic fungus Candida albicans is a frequent cause of mucosal infections.
Although the ability to transition from the yeast to the hypha morphology is essential for …

Vulvovaginal candidiasis (VVC), caused primarily by the human fungal pathogen Candida
albicans, results in significant quality-of-life issues for women worldwide. Candidalysin, a …

Millions of hibernating bats across North America have died from white-nose syndrome
(WNS), an emerging disease caused by a psychrophilic (cold-loving) fungus …

Immunocompromised individuals are at high risk of developing severe fungal infections with
high mortality rates, while fungal pathogens pose little risk to most healthy people. Poor …

Candida albicans is a deadly pathogen responsible for millions of mucosal and systemic
infections per year. The pathobiology of C. albicans is largely dependent on the damaging …

The fungal pathogen Candida albicans secretes the peptide toxin candidalysin, which
damages epithelial cells and drives an innate inflammatory response mediated by the …

During infection the host relies on pattern-recognition receptors to sense invading fungal
pathogens to launch immune defense mechanisms. While fungal recognition and immune …

BET inhibition or BRD4 depletion is a promising and attractive therapy for metastatic
melanoma; however, the mechanism is still unclear. Here, we indicated that BET inhibition …