Targeting glucose metabolism enzymes in cancer treatment: current and emerging strategies

Y Zhang, Q Li, Z Huang, B Li, EC Nice, C Huang, L Wei… - Cancers, 2022 - mdpi.com
Simple Summary Reprogramming of glucose metabolism is a hallmark of cancer and can be
targeted by therapeutic agents. Some metabolism regulators, such as ivosidenib and …

Ethnobotanical Uses, Phytochemistry, Toxicology, and Pharmacological Properties of Euphorbia neriifolia Linn. against Infectious Diseases: A Comprehensive …

A Sultana, MJ Hossain, MR Kuddus, MA Rashid… - Molecules, 2022 - mdpi.com
Medicinal plants have considerable potential as antimicrobial agents due to the presence of
secondary metabolites. This comprehensive overview aims to summarize the classification …

Chemico-pharmacological and computational studies of Ophiorrhiza fasciculata D. Don and Psychotria silhetensis Hook. f. focusing cytotoxic, thrombolytic, anti …

PT Rashid, MJ Hossain, MS Zahan, CM Hasan… - Heliyon, 2023 - cell.com
The current study sought to examine the pharmacological potentials of crude methanolic
extracts of Ophiorrhiza fasciculata and Psychotria silhetensis, as well as their various solvent …

Chemical profiling of volatile compounds of the essential oil of grey-leaved rockrose (Cistus albidus L.) and its antioxidant, anti-inflammatory, antibacterial, antifungal, and anticancer activity …

A Elbouzidi, M Taibi, S Laaraj, EH Loukili… - Frontiers in …, 2024 - frontiersin.org
Cistus albidus: L., also known as Grey-leaved rockrose and locally addressed as šṭab or
tûzzâla lbîḍa, is a plant species with a well-established reputation for its health-promoting …

[HTML][HTML] Chemical profiling and evaluation of toxicological, antioxidant, anti-inflammatory, anti-nociceptive and Tyrosinase inhibitory potential of Portulacaria afra using …

S Tabassum, S Ahmad, B Ali, F Usman… - Arabian Journal of …, 2023 - Elsevier
Abstract Portulacaria afra Jacq (Portulacaceae) is a medicinal plant used traditionally in the
treatment of pain and inflammation. This study aimed to evaluate the phytochemical …

From plant to chemistry: Sources of active opioid antinociceptive principles for medicinal chemistry and drug design

R Turnaturi, S Piana, S Spoto, G Costanzo, L Reina… - Molecules, 2023 - mdpi.com
Pain continues to be an enormous global health challenge, with millions of new untreated or
inadequately treated patients reported annually. With respect to current clinical applications …

Antimicrobial, antioxidant, and cytotoxic properties of endophytic fungi isolated from Thysanolaena maxima Roxb., Dracaena spicata Roxb. and Aglaonema …

N Hoque, ZR Khan, PT Rashid, MN Begum… - … Medicine and Therapies, 2023 - Springer
Background Endophytic fungi have recently been recognized as an impressive source of
natural biomolecules. The primary objective of the research was to isolate fungal …

Phyto-pharmacological and computational profiling of Bombax ceiba Linn. Leaves revealed pharmacological properties against oxidation, hyperglycemia, pain, and …

MA Taher, MJ Hossain, MS Zahan, MM Hasan… - Heliyon, 2024 - cell.com
The present study aimed to conduct phytochemical and pharmacological profiling of
methanolic crude extract of leaves of Bombax ceiba Linn. via experimental and …

Phenolic Constituents from Wendlandia tinctoria var. grandis (Roxb.) DC. Stem Deciphering Pharmacological Potentials against Oxidation, Hyperglycemia, and …

M Farzana, MJ Hossain, AM El-Shehawi, MAA Sikder… - Molecules, 2022 - mdpi.com
Wendlandia tinctoria var. grandis (Roxb.) DC.(Family: Rubiaceae) is a semi-evergreen
shrub distributed over tropical and subtropical Asia. The present research intended to …

In Vivo and In Silico Analgesic Activity of Ficus populifolia Extract Containing 2-O-β-D-(3′,4′,6′-Tri-acetyl)-glucopyranosyl-3-methyl Pentanoic Acid

HA Mohammed, AS Abouzied… - International Journal of …, 2023 - mdpi.com
Natural product-based structural templates have immensely shaped small molecule drug
discovery, and new biogenic natural products have randomly provided the leads and …