Opium alkaloids, biosynthesis, pharmacology and association with cancer occurrence

A Vadhel, S Bashir, AH Mir, M Girdhar… - Open …, 2023 - royalsocietypublishing.org
Papaver somniferum L.(Family: Papaveraceae) is a species well known for its diverse
alkaloids (100 different benzylisoquinoline alkaloids (BIAs)). L-tyrosine serves as a …

Opium as a carcinogen: A systematic review and meta-analysis

MZ Bidary, M Sahranavard, AA Rezayat… - …, 2021 - thelancet.com
Background Opium and its pyrolysates have been investigated as potential carcinogenic
material through several studies in different body systems; however, the results were …

Opium use and subsequent incidence of cancer: results from the Golestan Cohort Study

M Sheikh, R Shakeri, H Poustchi… - The Lancet Global …, 2020 - thelancet.com
Background Evidence is emerging for a role of opiates in various cancers. In this study, we
aimed to investigate the association between regular opium use and cancer incidence …

Opium use and risk of colorectal cancer: a multi-center case-referent study in Iran

M Hadji, M Marzban, H Rashidian… - Acta …, 2023 - Taylor & Francis
Background Opium use has been associated with an increased risk of cancers of the lung,
oesophagus, and pancreas, and it was recently classified by the International Agency for …

The Iranian study of opium and cancer (IROPICAN): rationale, design, and initial findings

M Hadji, H Rashidian, M Marzban, M Gholipour… - 2021 - trepo.tuni.fi
Background: The International Agency for Research on Cancer (IARC) recently classified
opium use as a Group 1 carcinogen. However, much remains to be studied on the relation …

[HTML][HTML] Opium use and head and neck cancers: a matched case-control study in Iran

H Alizadeh, A Naghibzadeh-Tahami… - Asian Pacific journal …, 2020 - ncbi.nlm.nih.gov
Background: Head and Neck (H and N) cancers include malignant tumors of the nasal
cavity, pharynx, paranasal sinuses, oral cavity, larynx and salivary glands. Opium use might …

Fifty Years of Research and One Conclusion: Opium Causes Cancer.

M Sheikh, F Kamangar… - Archives of Iranian …, 2020 - search.ebscohost.com
Abstract In September 2020, the International Agency for Research on Cancer (IARC)
announced that opium consumption causes cancer in humans--a conclusion drawn after …

Is opium use associated with an increased risk of lung cancer? A case-control study

A Naghibzadeh-Tahami, M Marzban… - BMC cancer, 2020 - Springer
Background In recent years, lung cancer (LC) incidence has increased in Iran. The use of
opium and its derivatives (O&D) has increased as well. This study aimed to investigate the …

Opium use as an independent risk factor for pancreatic cancer: A case-control study

A Naghibzadeh-Tahami, M Marzban… - Cancer …, 2021 - Elsevier
Background Pancreatic cancer (PC) is ranked as the seventh leading cause of cancer
deaths worldwide. The current study was conducted to explore the correlation between the …

Opium Use and Cancer Risk: A Comprehensive Systematic Review and Meta‐Analysis of Observational Studies

M Mansouri, S Naghshi, M Parsaeian… - … journal of clinical …, 2022 - Wiley Online Library
Background. Epidemiological studies have reported inconsistent associations between
opium use and cancer risk. We therefore conducted a systematic review and meta‐analysis …