Anthracyclines have been important and effective treatments against a number of cancers
since their discovery. However, their use in therapy has been complicated by severe side …

Doxorubicin belongs to the anthracycline chemical class of the drug and is one of the widely
used anticancer drugs. The common side effects of doxorubicin include vomiting, hair loss …

We present a novel glutathione-responsive amphiphilic drug self-delivery (DSD) micelle with
one-pot synthesis to synergistically address the problems of controlled drug release …

Polyprodrugs have been recognized as promising carrier-free drug delivery systems (DDSs)
for tumor chemotherapy in recent years, showing distinct superiority in comparison with the …

Doxorubicin, a widely used anthracycline anticancer agent, acts as a topoisomerase II
poison but can also form formaldehyde-mediated DNA adducts. This has led to the …

Novel anticancer compounds and their precision delivery systems are actively developed to
create potent and well‐tolerated anticancer therapeutics. Here, we report the synthesis of a …

Doxazolidine (doxaz) is a new anthracycline anticancer agent. While structurally similar to
doxorubicin (dox), doxaz acts via a distinct mechanism to selectively enhance anticancer …

Amphiphilic hyperbranched polyprodrugs (DOX‐S‐S‐PEG) with drug repeat units in
hydrophobic core linked by disulfide bonds were developed as drug self‐delivery systems …

The synthesis and tumor cell growth inhibition by doxazolidine carbamate prodrugs are
reported. The carbamates were designed for selective hydrolysis by one or more human …

Pharmaceutical compounds represent a class of emerging contaminants present in the
environment. Their intense (and increasing) use in human and veterinary medicine leads to …