Basic science breakthroughs in T-cell biology and immune–tumor cell interactions ushered
in a new era of cancer immunotherapy. Twenty years ago, cancer immunoediting was …

Criteria based on measurements of lesion diameter at CT have guided treatment with
historical therapies due to the strong association between tumor size and survival. Clinical …

Purpose The goal of this guideline/procedure standard is to assist nuclear medicine
physicians, other nuclear medicine professionals, oncologists or other medical specialists …

Immune checkpoint blockade (ICB) induces a remarkable and durable response in a subset
of cancer patients. However, most patients exhibit either primary or acquired resistance to …

Immunotherapy, represented by immune checkpoint inhibitors (ICIs), has made a
revolutionary difference in the treatment of malignant tumors, and considerably extended …

In recent years, various systemic immunotherapies have been developed for cancer
treatment, such as monoclonal antibodies (mABs) directed against immune checkpoints …

Immunotherapy with checkpoint inhibitors has prompted a major change not only in cancer
treatment but also in medical imaging. In parallel with the implementation of new drugs …

Objective. Patients with metastatic disease are followed throughout treatment with medical
imaging, and accurately assessing changes of individual lesions is critical to properly inform …

Immune checkpoint blockade using immune checkpoint inhibitors, including cytotoxic T-
lymphocyte-associated antigen–4 and programmed cell death protein-1/programmed cell …

The phenomenon of mixed/heterogenous treatment responses to cancer therapies within an
individual patient presents a challenging clinical scenario. Furthermore, the molecular basis …