Aging involves the systemic deterioration of all known cell types in most eukaryotes. Several
recently discovered compounds that extend the healthspan and lifespan of model organisms …

The past two decades have witnessed a global surge in the application of probiotics as
functional ingredients in food, animal feed, and pharmaceutical products. Among food …

Background: Parkinson's disease (PD) is caused by abnormal aggregation of α-synuclein
fibrils, called the Lewy bodies, in the central nervous system. Accumulating knowledge …

The microbiota of gut is the community of microbes living in an individual's gastrointestinal
tract. Several bacterial genera and species act in a concerted manner to establish metabolic …

It is generally accepted that carbohydrate fermentation results in beneficial effects for the
host because of the generation of short chain fatty acids, whereas protein fermentation is …

Low–molecular-weight metabolites produced by intestinal microbiota play a direct role in
health and disease. In this study, we analyzed the colonic luminal metabolome using …

The ageing process affects the human gut microbiota phylogenetic composition and its
interaction with the immune system. Age-related gut microbiota modifications are associated …

The human gut microbiota plays numerous roles in regulating host growth, the immune
system, and metabolism. Age-related changes in the gut environment lead to chronic …

Genetic, environmental, and lifestyle factors primarily determine the lifespan of humans.
From these, nutrition is a key component affecting our health, and several studies …

The intestine is the most densely colonized region of the body, inhabited by a diverse
community of microbes. The functional significance of the intestinal microbiota is not yet fully …