Prostacyclin for pulmonary arterial hypertension

H Barnes, HL Yeoh, T Fothergill… - Cochrane Database …, 2019 - cochranelibrary.com
Prostacyclin for pulmonary arterial hypertension - Barnes, H - 2019 | Cochrane Library Skip to
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[HTML][HTML] Pulmonary artery targeted therapy in treatment of COVID-19 related ARDS. Literature review

O Puk, A Nowacka, K Smulewicz, K Mocna… - Biomedicine & …, 2022 - Elsevier
Introduction The most grievous complication of the COVID-19 is the acute respiratory
distress syndrome. A specific, rescue treatment for rapidly deteriorating patients should …

Opportunities and challenges of pharmacotherapy for pulmonary arterial hypertension in children

CW Kam, FE Ruiz - Pediatric pulmonology, 2021 - Wiley Online Library
Pediatric pulmonary hypertension (PAH) is a rare disease that carries a poor prognosis if left
untreated. Although there are published guidelines for the treatment of children with …

Differential drug response in pulmonary arterial hypertension: The potential for precision medicine

E Miller, CUO Sampson, AA Desai… - Pulmonary …, 2023 - Wiley Online Library
Pulmonary arterial hypertension (PAH) is a rare, complex, and deadly cardiopulmonary
disease. It is characterized by changes in endothelial cell function and smooth muscle cell …

[HTML][HTML] Long-term experience and safety of transitioning from subcutaneous treprostinil to oral selexipag in the high-risk pulmonary hypertension patient: A case …

YH Ting, MW Yu, YJ Wu, SH Wu - Acta Cardiologica Sinica, 2023 - ncbi.nlm.nih.gov
Pulmonary arterial hypertension (PAH) is a rare and grave disease that affects the lungs and
heart. 1, 2 The primary goal of treatment is to delay disease progression, and as such …

[HTML][HTML] The use of selexipag, a prostacyclin receptor analog, for treatment of severe pulmonary artery hypertension during pregnancy, a case report

A Khan, K Hubel, K Brookfield, J Pak, G Allada… - … Medicine Case Reports, 2023 - Elsevier
Pregnancy in patients with pulmonary artery hypertension (PAH) is associated with high
mortality and morbidity. Despite the risks, more patients with PAH are becoming pregnant …

Is genetic variability in carboxylesterase-1 and carboxylesterase-2 drug metabolism an important component of personalized medicine?

SC Laizure, RB Parker - Xenobiotica, 2020 - Taylor & Francis
The carboxylesterase drug hydrolysis pathway has been used extensively to improve the
oral availability of drugs under the assumption that the high capacity and low substrate …

Transitioning intravenous epoprostenol to oral selexipag in idiopathic pulmonary arterial hypertension: a case report

A Alexandre, I Furtado, L Carvalho… - ESC Heart …, 2023 - Wiley Online Library
Intravenous (iv) prostacyclin is the cornerstone treatment in high‐risk pulmonary arterial
hypertension (PAH) patients. Selexipag is an orally available prostacyclin receptor agonist …

Pulmonary Arterial Hypertension in Connective Tissue Diseases Beyond Systemic Sclerosis

C Lewis, R Sanderson, N Vasilottos… - Heart Failure …, 2023 - heartfailure.theclinics.com
Pulmonary hypertension (PH) is a syndrome characterized by elevated pressures in the
pulmonary circulation resulting from a variety of conditions, as defined by the World Health …

NOTCH3 Mutations and CADASIL Phenotype in Pulmonary Arterial Hypertension Associated with Congenital Heart Disease.

R Jiang, K Lai, J Xu, X Feng, S Wang… - Congenital Heart …, 2022 - search.ebscohost.com
Background: The etiology of pulmonary arterial hypertension associated with congenital
heart disease (PAHCHD) is complicated and the phenotype is heterogeneous. Genetic …