[HTML][HTML] On having no head: cognition throughout biological systems
The central nervous system (CNS) underlies memory, perception, decision-making, and
behavior in numerous organisms. However, neural networks have no monopoly on the …
behavior in numerous organisms. However, neural networks have no monopoly on the …
Morphogenesis as Bayesian inference: A variational approach to pattern formation and control in complex biological systems
Recent advances in molecular biology such as gene editing [1], bioelectric recording and
manipulation [2] and live cell microscopy using fluorescent reporters [3],[4]–especially with …
manipulation [2] and live cell microscopy using fluorescent reporters [3],[4]–especially with …
[图书][B] Everything flows: towards a processual philosophy of biology
DJ Nicholson, J Dupré - 2018 - library.oapen.org
This collection of essays explores the metaphysical thesis that the living world is not
ontologically made up of substantial particles or things, as has often been assumed, but is …
ontologically made up of substantial particles or things, as has often been assumed, but is …
[HTML][HTML] The computational boundary of a “self”: developmental bioelectricity drives multicellularity and scale-free cognition
M Levin - Frontiers in psychology, 2019 - frontiersin.org
All epistemic agents physically consist of parts that must somehow comprise an integrated
cognitive self. Biological individuals consist of subunits (organs, cells, and molecular …
cognitive self. Biological individuals consist of subunits (organs, cells, and molecular …
[HTML][HTML] Most random gene expression signatures are significantly associated with breast cancer outcome
D Venet, JE Dumont, V Detours - PLoS computational biology, 2011 - journals.plos.org
Bridging the gap between animal or in vitro models and human disease is essential in
medical research. Researchers often suggest that a biological mechanism is relevant to …
medical research. Researchers often suggest that a biological mechanism is relevant to …
Knowing one's place: a free-energy approach to pattern regulation
Understanding how organisms establish their form during embryogenesis and regeneration
represents a major knowledge gap in biological pattern formation. It has been recently …
represents a major knowledge gap in biological pattern formation. It has been recently …
[HTML][HTML] How computational models can help unlock biological systems
GW Brodland - Seminars in cell & developmental biology, 2015 - Elsevier
With computation models playing an ever increasing role in the advancement of science, it is
important that researchers understand what it means to model something; recognize the …
important that researchers understand what it means to model something; recognize the …
Top-down models in biology: explanation and control of complex living systems above the molecular level
It is widely assumed in developmental biology and bioengineering that optimal
understanding and control of complex living systems follows from models of molecular …
understanding and control of complex living systems follows from models of molecular …
Molecular bioelectricity: how endogenous voltage potentials control cell behavior and instruct pattern regulation in vivo
M Levin - Molecular biology of the cell, 2014 - Am Soc Cell Biol
In addition to biochemical gradients and transcriptional networks, cell behavior is regulated
by endogenous bioelectrical cues originating in the activity of ion channels and pumps …
by endogenous bioelectrical cues originating in the activity of ion channels and pumps …
The algorithmic origins of life
SI Walker, PCW Davies - Journal of the Royal Society …, 2013 - royalsocietypublishing.org
Although it has been notoriously difficult to pin down precisely what is it that makes life so
distinctive and remarkable, there is general agreement that its informational aspect is one …
distinctive and remarkable, there is general agreement that its informational aspect is one …