Ubiquitin system mutations in neurological diseases
C Zenge, A Ordureau - Trends in Biochemical Sciences, 2024 - cell.com
Neuronal ubiquitin balance impacts the fate of countless cellular proteins, and its disruption
is associated with various neurological disorders. The ubiquitin system is critical for proper …
is associated with various neurological disorders. The ubiquitin system is critical for proper …
Friend or foe? Reciprocal regulation between E3 ubiquitin ligases and deubiquitinases
DL Bolhuis, MJ Emanuele… - Biochemical Society …, 2024 - portlandpress.com
Protein ubiquitination is a post-translational modification that entails the covalent attachment
of the small protein ubiquitin (Ub), which acts as a signal to direct protein stability …
of the small protein ubiquitin (Ub), which acts as a signal to direct protein stability …
Genome-wide association study meta-analysis of neurofilament light (NfL) levels in blood reveals novel loci related to neurodegeneration
Neurofilament light chain (NfL) levels in circulation have been established as a sensitive
biomarker of neuro-axonal damage across a range of neurodegenerative disorders …
biomarker of neuro-axonal damage across a range of neurodegenerative disorders …