Understanding the rules of life is one of the most important scientific endeavours and has
revolutionised both biology and biotechnology. Remarkable advances in observation …

In natural habitats, microbes form multispecies communities that commonly face rapidly
changing and highly competitive environments. Thus, phenotypic heterogeneity has evolved …

The slow maturation time of fluorescent proteins (FPs) limits the temporal accuracy of
measurements of rapid processes such as gene expression dynamics and effectively …

Extracellular vesicles are produced in all three domains of life, and their biogenesis has
common ancient origins in eukaryotes and archaea. Although bacterial vesicles were …

Fluorescent protein tags are fundamental tools used to visualize gene products and analyze
their dynamics in vivo. Recent advances in genome editing have expedited the precise …

Gene expression models, which are key towards understanding cellular regulatory
response, underlie observations of single-cell transcriptional dynamics. Although RNA …

Background: Leaping DNA read-and-write technologies, and extensive automation and
miniaturization are radically transforming the field of biological experimentation by providing …

Mechanosensitive processes often rely on adhesion structures to strengthen, or mature, in
response to applied loads. However, a limited understanding of how the molecular tensions …

Fluorescent protein (FP) maturation can limit the accuracy with which dynamic intracellular
processes are captured and reduce the in vivo brightness of a given FP in fast-dividing cells …

Dispersal of species is a fundamental ecological process in the evolution and maintenance
of biodiversity. Limited control over ecological parameters has hindered progress in …