Surface-associated microbial communities, called biofilms, are present in all environments.
Although biofilms play an important positive role in a variety of ecosystems, they also have …

Persisters are transiently tolerant variants that allow populations to avoid eradication by
antibiotic treatment. Their antibiotic tolerance is non-genetic, not inheritable and results from …

E. coli's hardiness, versatility, broad palate and ease of handling have made it the most
intensively studied and best understood organism on the planet. However, research on E …

Bacteria have evolved numerous means of survival in adverse environments with dormancy,
as represented by “persistence” and the “viable but nonculturable”(VBNC) state, now …

Internalization of pathogenic bacteria by macrophages results in formation of antibiotic-
tolerant persisters. These cells are maintained in a non-growing state for extended periods …

Insufficient development of new antibiotics and the rising resistance of bacteria to those that
we have are putting the world at risk of losing the most widely curative class of medicines …

Bacterial persisters are able to tolerate high levels of antibiotics and give rise to new
populations. Persister tolerance is generally attributed to minimally active cellular processes …

Staphylococcus aureus is an opportunistic pathogen capable of causing a variety of
diseases including osteomyelitis, endocarditis, infections of indwelling devices and wound …

Many bacterial pathogens can permanently colonize their host and establish either chronic
or recurrent infections that the immune system and antimicrobial therapies fail to eradicate …

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