Candida albicans is among the most prevalent fungal species of the human microbiota and
asymptomatically colonizes healthy individuals. However, it is also an opportunistic …

A major virulence attribute of Candida albicans is its ability to form biofilms, densely packed
communities of cells adhered to a surface. These biofilms are intrinsically resistant to …

In humans, microbial cells (including bacteria, archaea, and fungi) greatly outnumber host
cells. Candida albicans is the most prevalent fungal species of the human microbiota; this …

Neutrophils are critical for antifungal defense, but the mechanisms that clear hyphae and
other pathogens that are too large to be phagocytosed remain unknown. We found that …

Candida species cause frequent infections owing to their ability to form biofilms—surface-
associated microbial communities—primarily on implanted medical devices. Increasingly …

Biofilm formation is an important virulence factor for pathogenic fungi. Both yeasts and
filamentous fungi can adhere to biotic and abiotic surfaces, developing into highly organized …

Virulence of Candida is linked with its ability to form biofilms. Once established, biofilm
infections are nearly impossible to eradicate. Biofilm cells live immersed in a self-produced …

In healthcare settings, Candida spp. cause invasive disease with high mortality. The
overwhelming majority of cases are associated with the use of critically-needed medical …

Successful human colonizers such as Candida pathogens have evolved distinct strategies
to survive and proliferate within the human host. These include sophisticated mechanisms to …

A wide variety of fungi have demonstrated the ability to colonize surfaces and form biofilms.
Most studies on fungal biofilms have focused on Candida albicans and more recently …