As warned by Sir Alexander Fleming in his Nobel Prize address:“the use of antimicrobials
can, and will, lead to resistance”. Antimicrobial resistance (AMR) has recently increased due …

To combat the threat to human health and biosecurity from antimicrobial resistance, an
understanding of its mechanisms and drivers is needed. Emergence of antimicrobial …

Background Following the discovery and emergence of the plasmid-mediated colistin
resistance gene, mcr-1, the Chinese government formally banned colistin as an animal …

Antibiotic resistance is increasing in pathogenic microbial populations and is thus a major
threat to public health. The fate of a resistance mutation in pathogen populations is …

Large amounts of veterinary antibiotics are applied worldwide to farm animals and reach
agricultural fields by manure fertilization, where they might lead to an increased abundance …

Antibiotic resistance has become a global public health concern, rendering common
infections untreatable. Given the widespread occurrence, increasing attention is being …

Veterinary antibiotics (VAs) are used worldwide in animal farming as drugs to treat or
prevent diseases and serve as feed additives. VAs are usually poorly sorbed in the animal …

Swine feedlots are widely considered as a potential hotspot for promoting the dissemination
of antibiotic resistance genes (ARGs) in the environment. ARGs could enter the environment …

The usage of antibiotics in animal husbandry has promoted the development and
abundance of antibiotic resistance in farm environments. Manure has become a reservoir of …

The antibiotic ciprofloxacin is used extensively to treat a wide range of infections caused by
the opportunistic pathogen Pseudomonas aeruginosa. Due to its extensive use, the …