In this review, transition metal-catalyzed methodologies and applications that exploit C–C
bond cleavage of vinylcyclopropanes (VCPs) are summarized with a focus on cycloaddition …

The cleavage and reorganization of carbon− carbon bonds is an industrial key technology
for crude oil refining, carried out on a massive scale. In contrast, C− C bond cleavage …

First-row transition-metal-mediated reactions constitute an important and growing area of
research due to the low cost, low toxicity, and exceptional synthetic versatility of these …

Natural products containing eight-membered carbocycles constitute a class of structurally
intriguing and biologically important molecules such as the famous diterpenes taxol and …

Vinylcyclopropane (VCP) derivatives participate in a variety of transition-metal-catalyzed
multicomponent cycloadditions to produce five-to eight-membered carbocycles. Various …

Activated cyclopropanes show versatile reactivity and are therefore powerful building blocks
in organic chemistry and natural product synthesis. This review focuses on recent …

Conspectus Practical syntheses of natural products and their analogues with eight-
membered carbocyclic skeletons are important for medicinal and biological investigations …

Previously, we developed a rhodium-catalyzed [5+ 2+ 1] cycloaddition of ene–
vinylcyclopropanes (ene–VCPs) and carbon monoxide to synthesize eight-membered …

Covering: 2000–2018 In this review, we highlight recent examples of natural product total
syntheses employing transition metal-mediated/catalyzed carbonylative cyclization …

The Correct Structure of Aquatolide—Experimental Validation of a Theoretically-Predicted
Structural Revision | Journal of the American Chemical Society ACS ACS Publications C&EN …