Fluorescence imaging in the second near-infrared window (NIR-II) has become a prevalent
choice owing to its appealing advantages like deep penetration depth, low …

The field of cancer immunotherapy has shown significant growth, and researchers are now
focusing on effective strategies to enhance and prolong local immunomodulation. Injectable …

Delivery of chemotherapeutic medicines to solid tumors is critical for optimal therapeutic
success and minimal adverse effects. We mathematically developed a delivery method …

Immune checkpoint blockade (ICB) therapy is a revolutionary approach to treat cancers, but
still have limited clinical applications. Accumulating evidence pinpoints the …

We hypothesize that different routes of administration may lead to altered pharmacokinetics/
pharmacodynamics (PK/PD) behavior of antibody-drug conjugates (ADCs) and may help to …

Percutaneous cryoablation is a common clinical therapy for metastatic and primary cancer.
There are rare clinical reports of cryoablation inducing regression of distant metastases …

Cancer immunotherapy has revolutionized clinical cancer treatments by taking advantage of
the immune system to selectively and effectively target and kill cancer cells. However …

Systemic drug delivery is the current clinically preferred route for cancer therapy. However,
challenges associated with tumor localization and off-tumor toxic effects limit the clinical …

Chemical ablation was designed to inject chemical agents directly into solid tumors to kill
cells and is currently only used clinically for the palliative treatment of tumors. The …

Agonist CD40 monoclonal antibodies (mAb) is a promising immunotherapeutic agent for
cold‐to‐hot tumor immune microenvironment (TIME) conversion. Pancreatic ductal …