The pathophysiology of endometriosis and adenomyosis: tissue injury and repair

G Leyendecker, L Wildt, G Mall - Archives of gynecology and obstetrics, 2009 - Springer
Introduction This study presents a unifying concept of the pathophysiology of endometriosis
and adenomyosis. In particular, a physiological model is proposed that provides a …

A new concept of endometriosis and adenomyosis: tissue injury and repair (TIAR)

G Leyendecker, L Wildt - Hormone molecular biology and clinical …, 2011 - degruyter.com
Pelvic endometriosis, deeply infiltrating endometriosis and uterine adenomyosis share a
common pathophysiology and may be integrated into the physiological mechanism and new …

Chronic pelvic ischemia: contribution to the pathogenesis of lower urinary tract symptoms (LUTS): a new target for pharmacological treatment?

KE ANDERSSON, M Nomiya… - LUTS: Lower Urinary …, 2015 - Wiley Online Library
The incidence of lower urinary tract symptoms, including overactive bladder (OAB), is
continuing to rise, and is associated with a negative impact on quality of life and a heavy …

Update on overactive bladder therapeutic options

CP Babin, NT Catalano, DM Yancey… - American journal of …, 2024 - journals.lww.com
Background: Millions of Americans are burdened by overactive bladder (OAB) syndrome
and the psychogenic and economic hardships that accompany it. Several theories attempt to …

Urinary nerve growth factor but not prostaglandin E2 increases in patients with interstitial cystitis/bladder pain syndrome and detrusor overactivity

HT Liu, P Tyagi, MB Chancellor, HC Kuo - BJU international, 2010 - Wiley Online Library
Study Type–Aetiology (case series) Level of Evidence 4 OBJECTIVE To compare urinary
nerve growth factor (NGF) and prostaglandin E2 (PGE2) levels among patients with detrusor …

Pathophysiology of overactive bladder

E Meng, WY LIN, WC LEE… - LUTS: Lower Urinary …, 2012 - Wiley Online Library
Overactive bladder syndrome (OAB), characterized by urinary frequency, nocturia and
urgency with or without incontinence, is a widespread medical condition with significant …

Urinary biomarkers in patients with detrusor underactivity with and without bladder function recovery

SF Chen, YH Jiang, HC Kuo - International Urology and Nephrology, 2017 - Springer
Purpose Detrusor underactivity (DU) is frequently encountered in elderly patients. Part of
patients with DU might have bladder function recovery after treatment. This study …

Novel biomarkers for overactive bladder

R Cartwright, I Afshan, A Derpapas, G Vijaya… - Nature reviews …, 2011 - nature.com
Biomarkers constitute any objectively measurable indicator of a biological process. The
classic biomarker used in the diagnosis of overactive bladder (OAB) has been detrusor …

Potential biomarkers utilized to define and manage overactive bladder syndrome

HC KUO - LUTS: Lower Urinary Tract Symptoms, 2012 - Wiley Online Library
Clinical diagnosis of overactive bladder (OAB) syndrome has great variation and usually can
only be based on subjective symptoms. Measurement of urgency severity score in adjunct …

In the absence of overt urothelial damage, chondroitinase ABC digestion of the GAG layer increases bladder permeability in ovariectomized female rats

RE Hurst, S Van Gordon, K Tyler… - American Journal …, 2016 - journals.physiology.org
Loss of integrity of the protective impermeability barrier in the urothelium has been identified
as significant in bladder dysfunction. In this study, we tested the theory that the luminal layer …