Nanomaterials as signal amplification elements in DNA-based electrochemical sensing

L Wu, E Xiong, X Zhang, X Zhang, J Chen - Nano Today, 2014 - Elsevier
Signal amplification strategies have attracted considerable attention due to the growing
demands for ultrasensitive bioassays. Here, we summarize the latest developments in the …

The application of quantum dots, gold nanoparticles and molecular switches to optical nucleic-acid diagnostics

WR Algar, M Massey, UJ Krull - TrAC Trends in Analytical Chemistry, 2009 - Elsevier
This review discusses the application of quantum dots (QDs), gold nanoparticles (NPs), and
molecular switches in optical nucleic-acid diagnostics. The size-dependent optical …

Galvanic replacement-free deposition of Au on Ag for core–shell nanocubes with enhanced chemical stability and SERS activity

Y Yang, J Liu, ZW Fu, D Qin - Journal of the American Chemical …, 2014 - ACS Publications
We report a robust synthesis of Ag@ Au core–shell nanocubes by directly depositing Au
atoms on the surfaces of Ag nanocubes as conformal, ultrathin shells. Our success relies on …

Core–shell hybrid nanogels for integration of optical temperature-sensing, targeted tumor cell imaging, and combined chemo-photothermal treatment

W Wu, J Shen, P Banerjee, S Zhou - Biomaterials, 2010 - Elsevier
We report a class of core–shell structured hybrid nanogels to demonstrate the conception of
integrating the functional building blocks into a single nanoparticle system for …

Smart core− shell hybrid nanogels with Ag nanoparticle core for cancer cell imaging and gel shell for pH-regulated drug delivery

W Wu, T Zhou, A Berliner, P Banerjee… - Chemistry of …, 2010 - ACS Publications
Multifunctional nanoparticles that can provide long circulation and specific accumulation,
illuminate the targeted object, and intelligently dose the pathological zones will enable …

Molecularly mediated processing and assembly of nanoparticles: exploring the interparticle interactions and structures

SI Lim, CJ Zhong - Accounts of chemical research, 2009 - ACS Publications
The harnessing of the nanoscale properties of nanoparticles in most technological
applications requires the abilities of controlled processing and assembly, which has been an …

A smartphone-based electrochemical POCT for CEA based on signal amplification of Zr 6 MOFs

SS Shi, XJ Li, RN Ma, L Shang, W Zhang, HQ Zhao… - Lab on a Chip, 2024 - pubs.rsc.org
Carcinoembryonic antigen (CEA) is a biomarker of high expression in cancer cells. Highly
sensitive and selective detection of CEA holds significant clinical value in the diagnosis …

Double-shell gold nanoparticle-based DNA-carriers with poly-L-lysine binding surface

M Stobiecka, M Hepel - Biomaterials, 2011 - Elsevier
In view of the prospective applications of polyamine coatings in functional gold
nanoparticles for use as carriers in gene delivery systems, in tissue repair and as …

Resonance elastic light scattering (RELS) spectroscopy of fast non-Langmuirian ligand-exchange in glutathione-induced gold nanoparticle assembly

M Stobiecka, K Coopersmith, M Hepel - Journal of colloid and interface …, 2010 - Elsevier
The interactions of a biomolecule glutathione (GSH) with citrate-capped gold nanoparticles
(AuNP) have been investigated to evaluate the viability of a rapid GSH-capture by gold …

Sensing of transcription factor through controlled-assembly of metal nanoparticles modified with segmented DNA elements

YN Tan, X Su, Y Zhu, JY Lee - ACS nano, 2010 - ACS Publications
We have developed a unique metal nanoparticle (mNPs)-based assay to detect sequence-
specific interactions between transcription factor and its corresponding DNA-binding …