Abstract Magnesium (Mg 2+) is an essential ion to the human body, playing an instrumental
role in supporting and sustaining health and life. As the second most abundant intracellular …

Over the past decades, hypomagnesemia (serum Mg2+< 0.7 mmol/L) has been strongly
associated with type 2 diabetes mellitus (T2DM). Patients with hypomagnesemia show a …

Depression is a common condition, but current treatments are only effective in a subset of
individuals. To identify new treatment targets, we integrated depression genome-wide …

Context: Understanding the etiology, diagnosis, and symptoms of hypoparathyroidism may
help to improve quality of life and long-term disease outcomes. This paper summarizes the …

Genomic studies have identified hundreds of candidate genes near loci associated with risk
for schizophrenia. To define candidates and their functions, we mutated zebrafish orthologs …

Noncoding variants of presumed regulatory function contribute to the heritability of
neuropsychiatric disease. A total of 2,221 noncoding variants connected to risk for ten …

Magnesium is essential to the proper functioning of numerous cellular processes.
Magnesium ion (Mg 2+) deficits, as reflected in hypomagnesemia, can cause neuromuscular …

Abstract Magnesium (Mg2+) is the most prevalent divalent intracellular cation. As co-factor in
many enzymatic reactions, Mg2+ is essential for protein synthesis, energy production, and …

The CNNM/CorC family proteins are Mg2+ transporters that are widely distributed in all
domains of life. In bacteria, CorC has been implicated in the survival of pathogenic …

Magnesium is essential for cellular life, but how it is homeostatically controlled still remains
poorly understood. Here, we report that members of CNNM family, which have been …