The coral microbiome: towards an understanding of the molecular mechanisms of coral–microbiota interactions

AR Mohamed, MA Ochsenkühn… - FEMS Microbiology …, 2023 - academic.oup.com
Corals live in a complex, multipartite symbiosis with diverse microbes across kingdoms,
some of which are implicated in vital functions, such as those related to resilience against …

Toll-like receptors, associated biological roles, and signaling networks in non-mammals

L Nie, SY Cai, JZ Shao, J Chen - Frontiers in immunology, 2018 - frontiersin.org
The innate immune system is the first line of defense against pathogens, which is initiated by
the recognition of pathogen-associated molecular patterns (PAMPs) and endogenous …

Origins and diversification of animal innate immune responses against viral infections

RE Iwama, Y Moran - Nature ecology & evolution, 2023 - nature.com
Immune systems are of pivotal importance to any living organism on Earth, as they protect
the organism against deleterious effects of viral infections. Though the current knowledge …

Evolutionary origins of toll-like receptor signaling

JJ Brennan, TD Gilmore - Molecular biology and evolution, 2018 - academic.oup.com
Toll-like receptors (TLRs) are transmembrane pattern recognition receptors that are best
known for their roles in innate immunity for the detection of and defense against microbial …

Unlocking the complex cell biology of coral–dinoflagellate symbiosis: A model systems approach

MR Jacobovitz, EA Hambleton… - Annual Review of …, 2023 - annualreviews.org
Symbiotic interactions occur in all domains of life, providing organisms with resources to
adapt to new habitats. A prime example is the endosymbiosis between corals and …

Looking down on NF-κB

LM Williams, TD Gilmore - Molecular and Cellular Biology, 2020 - Am Soc Microbiol
The diversified NF-κB transcription factor family has been extensively characterized in
organisms ranging from flies to humans. However, homologs of NF-κB and many upstream …

Comparative analysis of the Pocillopora damicornis genome highlights role of immune system in coral evolution

R Cunning, RA Bay, P Gillette, AC Baker… - Scientific reports, 2018 - nature.com
Comparative analysis of the expanding genomic resources for scleractinian corals may
provide insights into the evolution of these organisms, with implications for their continued …

Cell biology of coral symbiosis: foundational study can inform solutions to the coral reef crisis

VM Weis - Integrative and Comparative Biology, 2019 - academic.oup.com
Coral reefs are faced with almost complete destruction by the end of the century due to
global warming unless humanity can cap global temperature rise. There is now a race to …

Innate immunity and cnidarian-Symbiodiniaceae mutualism

KM Mansfield, TD Gilmore - Developmental & Comparative Immunology, 2019 - Elsevier
The phylum Cnidaria (sea anemones, corals, hydra, jellyfish) is one the most distantly
related animal phyla to humans, and yet cnidarians harbor many of the same cellular …

Stony coral tissue loss disease intervention with amoxicillin leads to a reversal of disease‐modulated gene expression pathways

MS Studivan, RJ Eckert, E Shilling… - Molecular …, 2023 - Wiley Online Library
Stony coral tissue loss disease (SCTLD) remains an unprecedented disease outbreak due
to its high mortality rate and rapid spread throughout Florida's Coral Reef and wider …