There is a broad phenotypic spectrum of monogenic polycystic kidney diseases (PKD).
These disorders often involve cilia-related genes and lead to the development of fluid-filled …

Cystic kidney diseases, when broadly defined, have a wide differential diagnosis extending
from recessive diseases with a prenatal or pediatric diagnosis, to the most common …

Autosomal Dominant Polycystic Kidney Disease (ADPKD) stands as the most prevalent
hereditary renal disorder in humans, ultimately culminating in end-stage kidney disease …

The research of Mendel, born two centuries ago, still has many direct implications for our
everyday clinical work. He introduced the terms “dominant” and “recessive” characters and …

Cardiovascular disease (CVD) is a major cause of morbidity and mortality in autosomal
dominant polycystic kidney disease (ADPKD). While the current interventions are …

Abstract Background and Aims Polycystic kidney diseases (PKDs) are the most prevalent
inherited kidney disease. They are caused by pathogenic variants in genes encoding for …