SUMMARY Human herpesvirus 6 (HHV-6) is a betaherpesvirus that is closely related to
human cytomegalovirus. It was discovered in 1986, and HHV-6 literature has expanded …

Febrile seizures are the most common form of childhood seizures, occurring in 2 to 5% of
children in the United States. Most febrile seizures are considered simple, although those …

Human herpesvirus 6 variant A (HHV-6A) and human herpesvirus 6 variant B (HHV-6B) are
two closely related yet distinct viruses. These visuses belong to the Roseolovirus genus of …

Febrile seizure (FS) is the most common seizure disorder of childhood, and occurs in an age-
related manner. FS are classified into simple and complex. FS has a multifactorial …

Heterozygous loss-of-function mutations in the α subunit of the type I voltage-gated sodium
channel NaV1. 1 cause severe myoclonic epilepsy in infancy (SMEI), an infantile-onset …

SUMMARY Human herpesvirus 6A (HHV-6A) and human herpesvirus 6B (HHV-6B),
collectively termed HHV-6A/B, are neurotropic viruses that permanently infect most humans …

Studies of febrile seizures have been driven by two major enigmas: first, how these most
common of human seizures are generated by fever has not been known. Second …

Seizures induced by fever (febrile seizures) are the most common type of pathological brain
activity in infants and children. These febrile seizures and their potential contribution to the …

The role of viral infection in the etiology of febrile seizures is a relatively neglected field of
neurologic research. A National Institutes of Health Consensus Conference (1981) omitted …

This article provides an overview of the latest knowledge and understanding of childhood
febrile seizures. This review also discusses childhood febrile seizure occurrence, health …