Modulation of the hypothalamic-pituitary-adrenal axis by early life stress exposure

M Van Bodegom, JR Homberg… - Frontiers in cellular …, 2017 - frontiersin.org
Exposure to stress during critical periods in development can have severe long-term
consequences, increasing overall risk on psychopathology. One of the key stress response …

[HTML][HTML] Prenatal stressors in rodents: Effects on behavior

M Weinstock - Neurobiology of stress, 2017 - Elsevier
The current review focuses on studies in rodents published since 2008 and explores
possible reasons for any differences they report in the effects of gestational stress on various …

Neural mechanisms of stress resilience and vulnerability

TB Franklin, BJ Saab, IM Mansuy - Neuron, 2012 - cell.com
Exposure to stressful events can be differently perceived by individuals and can have
persistent sequelae depending on the level of stress resilience or vulnerability of each …

The consequences of early‐life adversity: neurobiological, behavioural and epigenetic adaptations

S Maccari, HJ Krugers… - Journal of …, 2014 - Wiley Online Library
During the perinatal period, the brain is particularly sensitive to remodelling by
environmental factors. Adverse early‐life experiences, such as stress exposure or …

Prenatal immune and endocrine modulators of offspring's brain development and cognitive functions later in life

S Schepanski, C Buss, IL Hanganu-Opatz… - Frontiers in …, 2018 - frontiersin.org
Milestones of brain development in mammals are completed before birth, which provide the
prerequisite for cognitive and intellectual performances of the offspring. Prenatal challenges …

Depression, obesity and their comorbidity during pregnancy: effects on the offspring's mental and physical health

N Cattane, K Räikkönen, R Anniverno… - Molecular …, 2021 - nature.com
Depression and obesity represent two of the most common complications during pregnancy
and are associated with severe health risks for both the mother and the child. Although …

Prenatal exposure to environmental insults and enhanced risk of developing Schizophrenia and Autism Spectrum Disorder: focus on biological pathways and …

N Cattane, J Richetto, A Cattaneo - Neuroscience & Biobehavioral …, 2020 - Elsevier
When considering neurodevelopmental disorders (NDDs), Schizophrenia (SZ) and Autism
Spectrum Disorder (ASD) are considered to be among the most severe in term of …

Prenatal stress and genetic risk: How prenatal stress interacts with genetics to alter risk for psychiatric illness

PW Abbott, SB Gumusoglu, J Bittle… - …, 2018 - Elsevier
Risk for neuropsychiatric disorders is complex and includes an individual's internal genetic
endowment and their environmental experiences and exposures. Embryonic development …

Sex, stress and steroids

Y Sze, PJ Brunton - European Journal of Neuroscience, 2020 - Wiley Online Library
The hypothalamo–pituitary–adrenal (HPA) axis plays a key role in the neuroendocrine
response to stress and in maintaining physiological homoeostasis. However, stress that is …

Strain-dependent effects of prenatal maternal immune activation on anxiety-and depression-like behaviors in offspring

S Babri, MH Doosti, AA Salari - Brain, behavior, and immunity, 2014 - Elsevier
There is converging evidence that prenatal maternal infection can increase the risk of
occurrence of neuropsychiatric disorders like schizophrenia, autism, anxiety and depression …