Abstract In 2003 Rubenstein and Merzenich hypothesized that some forms of Autism (ASD)
might be caused by a reduction in signal-to-noise in key neural circuits, which could be the …

In the cerebral cortex, GABAergic interneurons have evolved as a highly heterogeneous
collection of cell types that are characterized by their unique spatial and temporal …

Gene Ontology analyses of autism spectrum disorders (ASD) risk genes have repeatedly
highlighted synaptic function and transcriptional regulation as key points of convergence …

In the immature brain, GABA (γ-aminobutyric acid) is excitatory, and GABA-releasing
synapses are formed before glutamatergic contacts in a wide range of species and …

From early embryonic development to adulthood, GABA release participates in the
construction of the mammalian cerebral cortex. The maturation of GABAergic …

A highly diverse population of neocortical GABAergic inhibitory interneurons has been
implicated in multiple functions in information processing within cortical circuits. The diversity …

The promise of using reprogrammed human neurons for disease modeling and regenerative
medicine relies on the ability to induce patient-derived neurons with high efficiency and …

Although previous analyses indicate that neocortical neurons originate from the cortical
proliferative zone, evidence suggests that a subpopulation of neocortical interneurons …

The striatum is composed principally of GABAergic, medium spiny striatal projection neurons
(MSNs) that can be categorized based on their gene expression, electrophysiological …

Recent studies on the origin of cell populations in rodent and chicken embryonic brains
provide evidence for extensive tangential migration within the developing telencephalon. On …