Overactive bladder (OAB) is often treated with medications that block the cholinergic
receptors in the bladder (known as anticholinergics). The effect of this medication class on …

Background Patient stratification is the division of a patient population into distinct
subgroups based on the presence or absence of particular disease characteristics. As …

Alzheimer's Disease (AD) is a form of dementia that affects the memory, cognition, and motor
skills of patients. Extensive research has been done to develop accessible, cost-effective …

Background It is currently unknown whether exergaming is efficacious in people with major
neurocognitive disorder (MNCD) residing in long-term care facilities. This pilot randomized …

Disease-modifying pharmacotherapies for Alzheimer's Disease (AD) are currently in late-
stage clinical development; once approved, new healthcare infrastructures and services …

Electroconvulsive therapy (ECT) remains one of the most effective treatments for major
depressive disorder, but uncertainties persist regarding the cognitive tests to include in ECT …

Emerging digital tools have the potential to enable a new generation of qualitative and
quantitative assessment of cognitive performance. Moreover, the ubiquity of consumer …

Humans are a vision-dominated species; what we perceive depends on where we look.
Therefore, eye movements (EMs) are essential to our interactions with the environment, and …

The amyloid cascade model of Alzheimer's disease posits the primacy of amyloid beta
deposition preceding tau-mediated neurofibrillary tangle formation. The amyloid-tau …

As the focus of Alzheimer's disease (AD) therapeutic development shifts to the early stages
of the disease, the clinical endpoints used in drug trials, and how these might translate into …