Nanomedicine fight against antibacterial resistance: an overview of the recent pharmaceutical innovations

NE Eleraky, A Allam, SB Hassan, MM Omar - Pharmaceutics, 2020 - mdpi.com
Based on the recent reports of World Health Organization, increased antibiotic resistance
prevalence among bacteria represents the greatest challenge to human health. In addition …

Breakthroughs in bacterial resistance mechanisms and the potential ways to combat them

B Khameneh, R Diab, K Ghazvini, BSF Bazzaz - Microbial pathogenesis, 2016 - Elsevier
Multidrug-resistant (MDR) bacteria have increased at an alarming rate over recent decades
and cause serious problems. The emergence of resistant infections caused by these …

Drug delivery strategies for antibiofilm therapy

V Choi, JL Rohn, P Stoodley, D Carugo… - Nature Reviews …, 2023 - nature.com
Although new antibiofilm agents have been developed to prevent and eliminate pathogenic
biofilms, their widespread clinical use is hindered by poor biocompatibility and …

The role of nanotechnology in combating biofilm-based antibiotic resistance

B Malaekeh-Nikouei, BSF Bazzaz, E Mirhadi… - Journal of Drug Delivery …, 2020 - Elsevier
Many serious infections result from persistent microbial biofilms that do not respond to
conventional antibiotic therapy. Various therapeutic approaches have been developed and …

Current trends in development of liposomes for targeting bacterial biofilms

Z Rukavina, Ž Vanić - Pharmaceutics, 2016 - mdpi.com
Biofilm targeting represents a great challenge for effective antimicrobial therapy. Increased
biofilm resistance, even with the elevated concentrations of very potent antimicrobial agents …

Treating polymicrobial infections in chronic diabetic wounds

PJ Buch, Y Chai, ED Goluch - Clinical microbiology reviews, 2019 - Am Soc Microbiol
This review provides a comprehensive summary of issues associated with treating
polyclonal bacterial biofilms in chronic diabetic wounds. We use this as a foundation and …

Fusogenic Liposomes Increase the Antimicrobial Activity of Vancomycin Against Staphylococcus aureus Biofilm

AB Scriboni, VM Couto, LNM Ribeiro… - Frontiers in …, 2019 - frontiersin.org
Objective: The aim of the present study was to encapsulate vancomycin in different
liposomal formulations and compare the in vitro antimicrobial activity against …

Nanoparticulate antibiotic systems as antibacterial agents and antibiotic delivery platforms to fight infections

A Vassallo, MF Silletti, I Faraone… - Journal of …, 2020 - Wiley Online Library
Today's human society, product of decades of progress in all fields of knowledge, would
have been unimaginable without the discovery of antibiotics and more generally of …

Solid lipid nanoparticles carrying Eugenia caryophyllata essential oil: the novel nanoparticulate systems with broad‐spectrum antimicrobial activity

BS Fazly Bazzaz, B Khameneh… - Letters in applied …, 2018 - academic.oup.com
In this study, solid lipid nanoparticles containing Eugenia caryophyllata essential oil (SLN‐
EO) were prepared by high‐shear homogenization and ultrasound methods, and used to …

Investigation of the antibacterial activity and efflux pump inhibitory effect of co-loaded piperine and gentamicin nanoliposomes in methicillin-resistant Staphylococcus …

B Khameneh, M Iranshahy, M Ghandadi… - Drug development …, 2015 - Taylor & Francis
Objective: Antibiotic resistance has stimulated the research for developing novel strategies
that can prevent bacterial growth. Methicillin-resistant Staphylococcus aureus (MRSA) …