Obesity and cardiovascular disease: a scientific statement from the American Heart Association

TM Powell-Wiley, P Poirier, LE Burke, JP Després… - Circulation, 2021 - Am Heart Assoc
The global obesity epidemic is well established, with increases in obesity prevalence for
most countries since the 1980s. Obesity contributes directly to incident cardiovascular risk …

Obesity phenotypes, diabetes, and cardiovascular diseases

ME Piché, A Tchernof, JP Després - Circulation research, 2020 - Am Heart Assoc
This review addresses the interplay between obesity, type 2 diabetes mellitus, and
cardiovascular diseases. It is proposed that obesity, generally defined by an excess of body …

Obesity and the obesity paradox in heart failure

TB Horwich, GC Fonarow, AL Clark - Progress in cardiovascular diseases, 2018 - Elsevier
Obesity continues to be a public health problem in the general population, and also
significantly increases the risk for the development of new-onset heart failure (HF). However …

Modulation of Cardiac Arrhythmogenesis by Epicardial Adipose Tissue: JACC State-of-the-Art Review

AC Ernault, VMF Meijborg, R Coronel - Journal of the American College of …, 2021 - jacc.org
Obesity is a significant risk factor for arrhythmic cardiovascular death. Interactions between
epicardial adipose tissue (EAT) and myocytes are thought to play a key role in the …

Epicardial adipose tissue as a mediator of cardiac arrhythmias

KHK Patel, T Hwang, C Se Liebers… - American Journal of …, 2022 - journals.physiology.org
Obesity is associated with higher risks of cardiac arrhythmias. Although this may be partly
explained by concurrent cardiometabolic ill-health, growing evidence suggests that …

Pericardial, but not hepatic, fat by CT is associated with CV outcomes and structure: the multi-ethnic study of atherosclerosis

RV Shah, A Anderson, J Ding, M Budoff, O Rider… - JACC: Cardiovascular …, 2017 - jacc.org
Objectives: The study sought to determine the associations between local (pericardial) fat
and incident cardiovascular disease (CVD) events and cardiac remodeling independent of …

Association of volumetric epicardial adipose tissue quantification and cardiac structure and function

N Nerlekar, RG Muthalaly, N Wong… - Journal of the …, 2018 - Am Heart Assoc
Background Epicardial adipose tissue (EAT) is in immediate apposition to the underlying
myocardium and, therefore, has the potential to influence myocardial systolic and diastolic …

Evolutional change in epicardial fat and its correlation with myocardial diffuse fibrosis in heart failure patients

CK Wu, HY Tsai, MYM Su, YF Wu, JJ Hwang… - Journal of clinical …, 2017 - Elsevier
Objectives The aim of this study was to characterize the characteristics of epicardial fat (EAT)
in different stage heart failure (HF) patients and its relationship between cardiac fibrosis …

Abnormal peri-organ or intra-organ fat (APIFat) deposition: an underestimated predictor of vascular risk?

N Katsiki, VG Athyros… - Current vascular …, 2016 - ingentaconnect.com
Adipose tissue, a major endocrine organ, consists of brown and white adipocytes. Brown fat
may play a beneficial role in cardiometabolic disorders. Brown adipose tissue can also …

[HTML][HTML] Linking arrhythmias and adipocytes: insights, mechanisms, and future directions

MA Pabon, K Manocha, JW Cheung, JC Lo - Frontiers in Physiology, 2018 - frontiersin.org
Obesity and atrial fibrillation have risen to epidemic levels worldwide and may continue to
grow over the next decades. Emerging evidence suggests that obesity promotes atrial and …