Decellularized extracellular matrix-based bioinks for engineering tissue-and organ-specific microenvironments

BS Kim, S Das, J Jang, DW Cho - Chemical reviews, 2020 - ACS Publications
Biomaterials-based biofabrication methods have gained much attention in recent years.
Among them, 3D cell printing is a pioneering technology to facilitate the recapitulation of …

Methods of tissue decellularization used for preparation of biologic scaffolds and in vivo relevance

TJ Keane, IT Swinehart, SF Badylak - Methods, 2015 - Elsevier
Biologic scaffolds composed of extracellular matrix (ECM) are widely used in both preclinical
animal studies and in many clinical applications to repair and reconstruct tissues. Recently …

Tissue engineered bio‐blood‐vessels constructed using a tissue‐specific bioink and 3D coaxial cell printing technique: a novel therapy for ischemic disease

G Gao, JH Lee, J Jang, DH Lee… - Advanced functional …, 2017 - Wiley Online Library
Endothelial progenitor cells (EPCs) are a promising cell source for the treatment of several
ischemic diseases for their potentials in neovascularization. However, the application of …

An overview of tissue and whole organ decellularization processes

PM Crapo, TW Gilbert, SF Badylak - Biomaterials, 2011 - Elsevier
Biologic scaffold materials composed of extracellular matrix (ECM) are typically derived by
processes that involve decellularization of tissues or organs. Preservation of the complex …

Strategies for development of decellularized heart valve scaffolds for tissue engineering

Y Snyder, S Jana - Biomaterials, 2022 - Elsevier
Valvular heart diseases (VHDs) are currently treated using either mechanical or
bioprosthetic heart valves. Unfortunately, mechanical valves require lifelong anticoagulation …

Consequences of ineffective decellularization of biologic scaffolds on the host response

TJ Keane, R Londono, NJ Turner, SF Badylak - Biomaterials, 2012 - Elsevier
Biologic scaffold materials composed of extracellular matrix (ECM) are routinely used for a
variety of clinical applications. Despite known variations in tissue remodeling outcomes …

Decellularization systems and devices: State-of-the-art

D Choudhury, M Yee, ZLJ Sheng, A Amirul, MW Naing - Acta biomaterialia, 2020 - Elsevier
Extracellular matrix (ECM) is a natural biomaterial scaffold that provides biochemical and
structural support to its surrounding cells, forming tissue and respective organs. These ECM …

Applications of decellularized materials in tissue engineering: advantages, drawbacks and current improvements, and future perspectives

J Liao, B Xu, R Zhang, Y Fan, H Xie, X Li - Journal of Materials …, 2020 - pubs.rsc.org
Decellularized materials (DMs) are attracting more and more attention because of their
native structures, comparatively high bioactivity, low immunogenicity and good …

Extracellular matrix-based biomaterials and their influence upon cell behavior

MC Cramer, SF Badylak - Annals of biomedical engineering, 2020 - Springer
Biologic scaffold materials composed of allogeneic or xenogeneic extracellular matrix (ECM)
are commonly used for the repair and remodeling of injured tissue. The clinical outcomes …

Decellularized allogeneic and xenogeneic tissue as a bioscaffold for regenerative medicine: factors that influence the host response

SF Badylak - Annals of biomedical engineering, 2014 - Springer
Biologic scaffold materials composed of mammalian extracellular matrix (ECM) are prepared
by decellularization of source tissues harvested from either humans (allogeneic) or a variety …