Neuropsychiatric disorders, such as major depression, anxiety disorders, and post-traumatic
stress disorder, tend to be long-term conditions in whose development and maintenance …

The evolution of mass spectrometry (MS) and analytical techniques has led to the demand
for proteome analysis with high proteome coverage in single-shot measurements. Focus has …

Currently used antidepressant drugs target and facilitate the action of monoamine
neurotransmission. However, approximately 30% of patients do not respond to these drugs …

We recently reported that dopamine D1 receptor in the medial prefrontal cortex (mPFC) is
activated by subthreshold social defeat stress and suppresses the induction of depressive …

Many vegetable extracts, essential oils, and their main constituents are active on the Central
Nervous System (CNS). In fact, they have been used as sedatives, hypnotics, or tranquilizers …

Upon chronic stress, a fraction of individuals shows stress resilience, which can prevent long-
term mental dysfunction. The underlying molecular mechanisms are complex and have not …

Understanding the long-term effects of stress on brain function is crucial for understanding
the mechanisms of depression. The BALB/c mouse strain has high susceptibility to stress …

Severe and prolonged social stress induces mood and cognitive dysfunctions and
precipitates major depression. Neuroinflammation has been associated with chronic stress …

Despite the importance of lipid mediators in stress and depression and their link to
inflammation, the influence of stress on these mediators and their role in inflammation is not …

Stress caused by adverse and demanding conditions, a risk factor for mental illnesses,
induces adaptive or maladaptive neural and behavioral consequences, depending on the …