BACKGROUND Assisted reproduction technology (ART) is used worldwide, at increasing
rates, and data show that some adverse outcomes occur more frequently than following …

The in vitro tissue cultures are, beyond all difficulties, an essential tool in basic research as
well as in commercial applications. Numerous works devoted to plant tissue cultures proved …

The causes of embryonic arrest during pre-implantation development are poorly understood.
Attempts to correlate patterns of oocyte gene expression with successful embryo …

Genetic and environmental factors produce different levels of DNA damage in spermatozoa.
Usually, DNA-fragmented spermatozoa (DFS) are used with intracytoplasmic sperm …

A variety of evolutionary processes has led to the development of different organs to ensure
that internal fertilization occur successfully. Fallopian tubes are a particularly interesting …

Epigenetic mechanisms play critical roles in oogenesis and early embryo development in
mammals. One of these epigenetic mechanisms, DNA methylation is accomplished through …

The advent of in vitro fertilization (IVF) in animals and humans implies an extraordinary
change in the environment where the beginning of a new organism takes place. In mammals …

Epigenetics, and in particular imprinted genes, have a critical role in the development and
function of the placenta, which in turn has a central role in the regulation of fetal growth and …

Negative energy balance (NEB) during early lactation in dairy cows leads to an altered
metabolic state that has major effects on the production of IGF family members. Low IGF-I …

Previously, we have shown that a maternal low protein diet, fed exclusively during the
preimplantation period of mouse development (Emb-LPD), is sufficient to induce by the …