Cationic dinitrosyl iron complexes with thiourea exhibit selective toxicity to brain tumor cells in vitro

NA Sanina, IV Sulimenkov, NS Emel'yanova… - Dalton …, 2022 - pubs.rsc.org
The cytotoxic activity of a series of dinitrosyl iron complexes (DNICs) with thioureas against
cells of different origin has been studied in this work. The cytotoxicity of the studied DNICs …

Effect of albumin on the transformation of dinitrosyl iron complexes with thiourea ligands

ОV Pokidova, VB Luzhkov, NS Emel'yanova… - Dalton …, 2020 - pubs.rsc.org
Interaction and transformation of the mononuclear cationic dinitrosyl iron complex [Fe (SC
(NH2) 2) 2 (NO) 2]+(complex 1) upon binding with bovine serum albumin (BSA) have been …

A new member of the cationic dinitrosyl iron complexes family incorporating N-ethylthiourea is effective against human HeLa and MCF-7 tumor cell lines

NA Sanina, NY Shmatko, DV Korchagin… - Journal of …, 2016 - Taylor & Francis
A new analog of the active site of mononuclear dinitrosyl [1Fe–2S] proteins,[C3N2H8SFe
(NO) 2Cl][Fe (NO) 2 (C3N2H8S) 2]+ Cl−(I), has been synthesized by reacting NO with an …

Nitrosyl iron complexes with enhanced NO donating ability: synthesis, structure and properties of a new type of salt with the DNIC cations [Fe (SC (NH 2) 2) 2 (NO) 2]+

NA Sanina, SM Aldoshin, DV Korchagin… - New Journal of …, 2015 - pubs.rsc.org
Novel nitrosyl iron complexes [Fe (SC (NH2) 2) 2 (NO) 2] 2SO4· H2O (I) and [Fe (SC (NH2)
2) 2 (NO) 2] 2 [Fe2 (S2O3) 2 (NO) 4](II) have been synthesized via the reactions of FeSO4 …

Insight into the Electronic Structure of Biomimetic Dinitrosyliron Complexes (DNICs): Toward the Syntheses of Amido-Bridging Dinuclear DNICs

CY Tung, YT Tseng, TT Lu, WF Liaw - Inorganic Chemistry, 2021 - ACS Publications
The ubiquitous function of nitric oxide (NO) guided the biological discovery of the natural
dinitrosyliron unit (DNIU)[Fe (NO) 2] as an intermediate/end product after Fe nitrosylation of …

Investigation of the interaction of the cationic nitrosyl iron complex [Fe (SC (NH2) 2) 2 (NO) 2]+ with molecular oxygen

NS Emel'yanova, LG Gutsev, OV Pokidova… - Inorganica Chimica …, 2021 - Elsevier
The interaction of a nitrosyl iron complex with molecular oxygen was studied with Density
Functional Theory. On the basis our analysis of the geometric and electronic structure of the …

Features of the decomposition of the nitrosyl iron complex with thiourea ligands under aerobic conditions: experiment and kinetic and quantum chemical modeling

OV Pokidova, BL Psikha, NS Emel'yanova… - Russian Chemical …, 2022 - Springer
The reaction of oxygen with the nitrosyl iron complex [Fe (SC (NH2) 2) 2 (NO) 2]+(complex
1) was studied. According to the results obtained, three main directions of transformation of …

Features of the decomposition of cationic nitrosyl iron complexes with N-ethylthiourea and penicillamine ligands in the presence of albumin

OV Pokidova, AY Kormukhina, AI Kotelnikov… - Inorganica Chimica …, 2021 - Elsevier
In this work, transformations of two cationic dinitrosyl iron complexes (DNICs), namely,
mononuclear with N-ethylthiourea ligands [Fe (SC (NH 2)(NHC 2 H 5)) 2 (NO) 2]+ Cl−∙[Fe …

Transformation of mononuclear dinitrosyl iron complex (DNIC) with thiourea in glutathione aqueous solution

ОV Pokidova, NS Emel'yanova, BL Psikha… - Journal of Molecular …, 2019 - Elsevier
In this work, transformation of DNIC with thiourea ligands,[Fe (SС (NH 2) 2) 2 (NO) 2] Сl∙ H 2
O (I), in an aqueous buffer solution at neutral pH and in the presence of reduced glutathione …

The cationic dinitrosyl iron complexes family with thiocarbamide derivatives: Synthesis, structure and properties in the solid state

NY Shmatko, DV Korchagin, GV Shilov, NS Ovanesyan… - Polyhedron, 2017 - Elsevier
Three new compounds of formulas [Fe (SC (NH 2) 2) 2 (NO) 2] 2 (Cl)(ClO 4)· H 2 O (I),[Fe
(SC (NH 2) 2) 2 (NO) 2] ClO 4 (II) and [Fe (SC (NHCH 3) 2) 2 (NO) 2] BF 4 (III), which are …