Omicron: what makes the latest SARS-CoV-2 variant of concern so concerning?

C Jung, D Kmiec, L Koepke, F Zech, T Jacob… - Journal of …, 2022 - Am Soc Microbiol
Emerging strains of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the
causative agent of the coronavirus disease 2019 (COVID-19) pandemic, that show …

Interferon antagonists encoded by SARS-CoV-2 at a glance

JH Lee, L Koepke, F Kirchhoff, KMJ Sparrer - Medical microbiology and …, 2023 - Springer
The innate immune system is a powerful barrier against invading pathogens. Interferons
(IFNs) are a major part of the cytokine-mediated anti-viral innate immune response. After …

SARS-CoV-2 variants of concern hijack IFITM2 for efficient replication in human lung cells

R Nchioua, A Schundner, D Kmiec… - Journal of …, 2022 - Am Soc Microbiol
It has recently been shown that an early SARS-CoV-2 isolate (NL-02-2020) hijacks
interferon-induced transmembrane proteins (IFITMs) for efficient replication in human lung …

SARS-CoV-2 Omicron variant virus isolates are highly sensitive to interferon treatment

D Bojkova, T Rothenburger, S Ciesek, MN Wass… - Cell discovery, 2022 - nature.com
Dear Editor, The SARS-CoV-2 Omicron variant (B. 1.1. 529) causes less severe disease
than previous SARS-CoV-2 variants, although immune protection provided by vaccinations …

Neutralization heterogeneity of circulating SARS-CoV-2 variants to sera elicited by a vaccinee or convalescent

M Zhang, Y Gong, S Jiao - Future Virology, 2022 - Taylor & Francis
COVID-19, which was first reported in December 2019 in China, has caused a global
outbreak. Five variants of concern (VOCs) have been identified in different countries since …

SARS-CoV-2 variants of concern remain dependent on IFITM2 for efficient replication in human lung cells

R Nchioua, A Schundner, D Kmiec, C Prelli-Bozzo… - bioRxiv, 2021 - biorxiv.org
It has recently been shown that an early SARS-CoV-2 isolate (NL-02-2020) hijacks
interferon-induced transmembrane proteins (IFITMs) for efficient replication in human cells …

[PDF][PDF] 2. A comparison of the temperature-dependent replicative fitness, infectivity, and cellular tropism of delta and delta plus SARS-CoV-2 variants circulating in …

JD Resnick, E Anaya, Z Ma… - VIRAL AND HOST …, 2023 - jscholarship.library.jhu.edu
Previous work has compared the Spike proteins of Alpha and Delta and their ability to
facilitate replication, fusion, and binding to ACE2. Overall, it appears that Delta viruses have …