Background The increased adoption of the internet, social media, wearable devices, e-
health services, and other technology-driven services in medicine and healthcare has led to …

Big data is important to new developments in global clinical science that aim to improve the
lives of patients. Technological advances have led to the regular use of structured electronic …

Background Large-scale and contemporary population-based studies of heart failure
incidence are needed to inform resource planning and research prioritisation but current …

Abstract The Clinical Practice Research Datalink (CPRD) is an ongoing primary care
database of anonymised medical records from general practitioners, with coverage of over …

Objectives To examine temporal trends in sex and age specific incidence of self harm in
children and adolescents, clinical management patterns, and risk of cause specific mortality …

Routinely collected health data, obtained for administrative and clinical purposes without
specific a priori research goals, are increasingly used for research. The rapid evolution and …

Objective Several recent observational studies have linked metabolic comorbidities to an
increased risk from COVID-19. Here we investigated whether women with PCOS are at an …

Background The burden of psoriasis across many world regions is high and there is a
recognized need to better understand the epidemiology of this common skin disorder …

Abstract Objective Electronic health records (EHRs) are a rich source of information on
human diseases, but the information is variably structured, fragmented, curated using …

Background: To examine the association between the degree of risk factor control and
cardiovascular disease (CVD) risk in type 2 diabetes and to assess if the presence of cardio …