An overview of microRNAs: Biology, functions, therapeutics, and analysis methods

K Saliminejad, HR Khorram Khorshid… - Journal of cellular …, 2019 - Wiley Online Library
MicroRNAs (miRNAs) are a class of small noncoding RNAs, which function in
posttranscriptional regulation of gene expression. They are powerful regulators of various …

Trends in the development of miRNA bioinformatics tools

L Chen, L Heikkinen, C Wang, Y Yang… - Briefings in …, 2019 - academic.oup.com
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression via
recognition of cognate sequences and interference of transcriptional, translational or …

Ensembl 2021

KL Howe, P Achuthan, J Allen, J Allen… - Nucleic acids …, 2021 - academic.oup.com
Abstract The Ensembl project (https://www. ensembl. org) annotates genomes and
disseminates genomic data for vertebrate species. We create detailed and comprehensive …

miRNet 2.0: network-based visual analytics for miRNA functional analysis and systems biology

L Chang, G Zhou, O Soufan, J Xia - Nucleic acids research, 2020 - academic.oup.com
Abstract miRNet is an easy-to-use, web-based platform designed to help elucidate
microRNA (miRNA) functions by integrating users' data with existing knowledge via network …

Ensembl 2020

AD Yates, P Achuthan, W Akanni, J Allen… - Nucleic acids …, 2020 - academic.oup.com
Abstract The Ensembl (https://www. ensembl. org) is a system for generating and distributing
genome annotation such as genes, variation, regulation and comparative genomics across …

Therapeutic target database 2020: enriched resource for facilitating research and early development of targeted therapeutics

Y Wang, S Zhang, F Li, Y Zhou, Y Zhang… - Nucleic acids …, 2020 - academic.oup.com
Abstract Knowledge of therapeutic targets and early drug candidates is useful for improved
drug discovery. In particular, information about target regulators and the patented …

miRBase: from microRNA sequences to function

A Kozomara, M Birgaoanu… - Nucleic acids …, 2019 - academic.oup.com
Abstract miRBase catalogs, names and distributes microRNA gene sequences. The latest
release of miRBase (v22) contains microRNA sequences from 271 organisms: 38 589 …

NetworkAnalyst 3.0: a visual analytics platform for comprehensive gene expression profiling and meta-analysis

G Zhou, O Soufan, J Ewald, REW Hancock… - Nucleic acids …, 2019 - academic.oup.com
The growing application of gene expression profiling demands powerful yet user-friendly
bioinformatics tools to support systems-level data understanding. NetworkAnalyst was first …

OmicsNet 2.0: a web-based platform for multi-omics integration and network visual analytics

G Zhou, Z Pang, Y Lu, J Ewald, J Xia - Nucleic acids research, 2022 - academic.oup.com
Researchers are increasingly seeking to interpret molecular data within a multi-omics
context to gain a more comprehensive picture of their study system. OmicsNet (www …

RNAcentral 2021: secondary structure integration, improved sequence search and new member databases

Nucleic acids research, 2021 - academic.oup.com
RNAcentral is a comprehensive database of non-coding RNA (ncRNA) sequences that
provides a single access point to 44 RNA resources and> 18 million ncRNA sequences from …