Pulmonary fibrosis as a result of acute lung inflammation: molecular mechanisms, relevant in vivo models, prognostic and therapeutic approaches

IA Savin, MA Zenkova, AV Sen'kova - International journal of molecular …, 2022 - mdpi.com
Pulmonary fibrosis is a chronic progressive lung disease that steadily leads to lung
architecture disruption and respiratory failure. The development of pulmonary fibrosis is …

Pathogenic cellular and molecular mediators in lupus nephritis

C Mohan, T Zhang, C Putterman - Nature Reviews Nephrology, 2023 - nature.com
Kidney involvement in patients with systemic lupus erythematosus—lupus nephritis (LN)—is
one of the most important and common clinical manifestations of this disease and occurs in …

2019 update of the joint European League Against Rheumatism and European Renal Association–European Dialysis and Transplant Association (EULAR/ERA …

A Fanouriakis, M Kostopoulou, K Cheema… - Annals of the …, 2020 - ard.bmj.com
Objective To update the 2012 EULAR/ERA–EDTA recommendations for the management of
lupus nephritis (LN). Methods Following the EULAR standardised operating procedures, a …

Renal fibrosis in lupus nephritis

S Sciascia, M Cozzi, A Barinotti, M Radin… - International Journal of …, 2022 - mdpi.com
Fibrosis can be defined as a pathological process in which deposition of connective tissue
replaces normal parenchyma. The kidney, like any organ or tissue, can be impacted by this …

[HTML][HTML] The glomerular crescent: triggers, evolution, resolution, and implications for therapy

L Anguiano, R Kain, HJ Anders - Current Opinion in Nephrology …, 2020 - journals.lww.com
The glomerular crescent: triggers, evolution, resolution, an... : Current Opinion in Nephrology
and Hypertension The glomerular crescent: triggers, evolution, resolution, and implications for …

Advances in lupus nephritis pathogenesis: from bench to bedside

B Obrișcă, B Sorohan, L Tuță, G Ismail - International journal of …, 2021 - mdpi.com
Systemic lupus erythematosus (SLE) is the prototype of autoimmune disorders caused by a
loss of tolerance to endogenous nuclear antigens triggering an aberrant autoimmune …

The Asia-Pacific League of Associations for Rheumatology consensus statements on the management of systemic lupus erythematosus

CC Mok, L Hamijoyo, N Kasitanon, S Chen… - The Lancet …, 2021 - thelancet.com
Systemic lupus erythematosus (SLE) is prevalent in Asia and carries a variable prognosis
among patients across the Asia-Pacific region, which could relate to access to health care …

Lupus nephritis: challenges and progress

A Davidson, C Aranow, M Mackay - Current Opinion in …, 2019 - journals.lww.com
The collaborative efforts of patients, clinical and translational researchers, the
pharmaceutical industry and funding sources are needed to advance therapies for lupus …

Association of urine sCD163 with proliferative lupus nephritis, fibrinoid necrosis, cellular crescents and intrarenal M2 macrophages

T Zhang, H Li, K Vanarsa, G Gidley, CC Mok… - Frontiers in …, 2020 - frontiersin.org
CD163 is a marker for alternatively activated macrophages, which have been implicated in
the pathogenesis of lupus nephritis (LN). In our preliminary screening of urine proteins in …

microRNAs in chronic kidney disease

H Zhao, SX Ma, YQ Shang, HQ Zhang, W Su - Clinica chimica acta, 2019 - Elsevier
Chronic kidney disease (CKD) results in high morbidity and mortality worldwide causing a
huge socioeconomic burden. MicroRNA (miRNA) exert critical regulatory functions by …