Tuberculosis: an overview of the immunogenic response, disease progression, and medicinal chemistry efforts in the last decade toward the development of potential …

A Sharma, M De Rosa, N Singla, G Singh… - Journal of medicinal …, 2021 - ACS Publications
Tuberculosis (TB) is a slow growing, potentially debilitating disease that has plagued
humanity for centuries and has claimed numerous lives across the globe. Concerted efforts …

Effectiveness of real-time polymerase chain reaction assay for the detection of Mycobacterium tuberculosis in pathological samples: a systematic review and meta …

EO Babafemi, BP Cherian, L Banting, GA Mills… - Systematic reviews, 2017 - Springer
Background Rapid and accurate diagnosis of tuberculosis (TB) is key to manage the
disease and to control and prevent its transmission. Many established diagnostic methods …

Electrochemical aptasensor using optimized surface chemistry for the detection of Mycobacterium tuberculosis secreted protein MPT64 in human serum

M Sypabekova, P Jolly, P Estrela… - Biosensors and …, 2019 - Elsevier
Tuberculosis (TB) remains one of the leading causes of mortality worldwide. There is a great
need for the development of diagnostic tests, which are reliable, sensitive, stable, and low …

Detection of Mycobacterium tuberculosis Complex in Sputum Samples Using Droplet Digital PCR Targeting mpt64

YW Aung, K Faksri, A Sangka, K Tomanakan… - Pathogens, 2023 - mdpi.com
Tuberculosis (TB) is one of the top 10 causes of death worldwide. It is challenging to find
methods of diagnosis of active pulmonary TB that are sensitive enough to detect cases for …

Laboratory tools for the direct detection of bacterial respiratory infections and antimicrobial resistance: a scoping review

OO Adewusi, CL Waldner… - Journal of …, 2024 - journals.sagepub.com
Rapid laboratory tests are urgently required to inform antimicrobial use in food animals. Our
objective was to synthesize knowledge on the direct application of long-read metagenomic …

Diagnosis of tuberculosis: nanodiagnostics approaches

AK Gupta, A Singh, S Singh - NanoBioMedicine, 2020 - Springer
Tuberculosis (TB) remains one of the most devastating infectious diseases worldwide. The
burden of TB is alarmingly high in developing countries, where diagnosis latent TB infection …

Role of the clinical microbiology laboratory in antimicrobial stewardship

E Bouza, P Muñoz, A Burillo - Medical Clinics, 2018 - medical.theclinics.com
The support offered by a microbiology department to an antimicrobial stewardship program
depends on the department's infrastructure and functioning. Among the factors that affect the …

[HTML][HTML] Description, validation, and review of a decade of experience with a laboratory-developed PCR test for detection of Mycobacterium tuberculosis complex in …

SP Buckwalter, BJ Connelly, LK Louison… - Journal of Clinical …, 2022 - Elsevier
Rapid detection of Mycobacterium tuberculosis complex directly from clinical specimens is
critical for patient care. Mycobacterial culture requires days to weeks for results and …

[HTML][HTML] Detection of Mycobacterium chelonae, Mycobacterium abscessus group, and Mycobacterium fortuitum complex by a multiplex real-time PCR directly from …

TT Rocchetti, S Silbert, A Gostnell, C Kubasek… - The Journal of Molecular …, 2017 - Elsevier
A new multiplex PCR test was designed to detect Mycobacterium chelonae, Mycobacterium
abscessus group, and Mycobacterium fortuitum complex on the BD MAX System. A total of …

Molecular detection of Mycobacterium tuberculosis in pulmonary and extrapulmonary samples in a hospital-based study

KI Goud, M Kavitha, A Mahalakshmi, R Vempati… - African Health …, 2020 - ajol.info
Objective: Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a
deadly infectious disease. India contributes to one-third of the global TB burden. However …