Consensus guidelines for the use and interpretation of angiogenesis assays

P Nowak-Sliwinska, K Alitalo, E Allen, A Anisimov… - Angiogenesis, 2018 - Springer
The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …

Retinal vasculature development in health and disease

S Selvam, T Kumar, M Fruttiger - Progress in retinal and eye research, 2018 - Elsevier
Abstract Development of the retinal vasculature is based on highly coordinated signalling
between different cell types of the retina, integrating internal metabolic requirements with …

Senescence-associated secretory phenotype contributes to pathological angiogenesis in retinopathy

M Oubaha, K Miloudi, A Dejda, V Guber… - Science translational …, 2016 - science.org
Pathological angiogenesis is the hallmark of diseases such as cancer and retinopathies.
Although tissue hypoxia and inflammation are recognized as central drivers of vessel …

Retinal lipid and glucose metabolism dictates angiogenesis through the lipid sensor Ffar1

JS Joyal, Y Sun, ML Gantner, Z Shao, LP Evans… - Nature medicine, 2016 - nature.com
Tissues with high metabolic rates often use lipids, as well as glucose, for energy, conferring
a survival advantage during feast and famine. Current dogma suggests that high-energy …

The phase changes of M1/M2 phenotype of microglia/macrophage following oxygen-induced retinopathy in mice

J Li, S Yu, X Lu, K Cui, X Tang, Y Xu, X Liang - Inflammation Research, 2021 - Springer
Objective Microglia/macrophage activation is previously reported to be involved in various
ocular diseases. However, the separate role of M1/M2 phenotype microglia/macrophage in …

Pharmacokinetics of bevacizumab and its effects on serum VEGF and IGF-1 in infants with retinopathy of prematurity

L Kong, AR Bhatt, AB Demny, DK Coats… - … & visual science, 2015 - iovs.arvojournals.org
Purpose.: To measure serum levels of bevacizumab and to compare serum levels of free
vascular endothelial growth factor (VEGF) and insulin-like growth factor-1 (IGF-1) in infants …

Ischemic neurons prevent vascular regeneration of neural tissue by secreting semaphorin 3A

JS Joyal, N Sitaras, F Binet, JC Rivera… - Blood, The Journal …, 2011 - ashpublications.org
The failure of blood vessels to revascularize ischemic neural tissue represents a significant
challenge for vascular biology. Examples include proliferative retinopathies (PRs) such as …

Importance of early postnatal weight gain for normal retinal angiogenesis in very preterm infants: a multicenter study analyzing weight velocity deviations for the …

C Wu, C Löfqvist, LEH Smith… - Archives of …, 2012 - jamanetwork.com
Objective To assess WINROP (https://winrop. com), an algorithm using postnatal weight
measurements, as a tool for the prediction of retinopathy of prematurity (ROP) in a large …

Vascular permeability in retinopathy is regulated by VEGFR2 Y949 signaling to VE-cadherin

RO Smith, T Ninchoji, E Gordon, H André, E Dejana… - Elife, 2020 - elifesciences.org
Edema stemming from leaky blood vessels is common in eye diseases such as age-related
macular degeneration and diabetic retinopathy. Whereas therapies targeting vascular …

The biology of retinopathy of prematurity: how knowledge of pathogenesis guides treatment

LE Smith, AL Hard, A Hellström - Clinics in perinatology, 2013 - perinatology.theclinics.com
Retinopathy of prematurity (ROP) occurs because the retina of a preterm infant at birth is
incompletely vascularized, and if the postnatal environment does not match the in utero …