Kawasaki disease is an acute febrile illness and systemic vasculitis of unknown aetiology
that predominantly afflicts young children, causes coronary artery aneurysms and can result …

Antibodies can impact pathogens in the presence or in the absence of effector cells or
effector molecules such as complement, and experiments can often sort out with precision …

Kawasaki disease is an acute febrile illness and systemic vasculitis of unknown aetiology
that predominantly afflicts young children, causes coronary artery aneurysms and can result …

We analyzed a genetic polymorphism of Fcγ receptor IIIa (CD16) that is present on position
158 (Phe or Val) in the membrane-proximal, IgG-binding domain. With a polymerase chain …

A novel polymorphism in the extracellular domain 2 (EC2) of FcgammaRIIIA affects ligand
binding by natural killer (NK) cells and monocytes from genotyped homozygous normal …

The complement system comprises several fluid-phase and membrane-associated proteins.
Under physiological conditions, activation of the fluid-phase components of complement is …

The only natural reservoir of Neisseria meningitidis is the human nasopharyngeal mucosa.
Depending on age, climate, country, socioeconomic status, and other factors, approximately …

The pentraxins are an ancient family of proteins with a unique architecture found as far back
in evolution as the Horseshoe crab. In humans the two members of this family are C‐reactive …

Despite considerable advances in the understanding of the pathogenesis of meningococcal
disease, this infection remains a major cause of morbidity and mortality globally. The role of …

Leukocyte Fcγ receptors (FcγR) confer potent cellular effector functions to the specificity of
IgG. FcγR‐induced leukocyte functions, including antibody‐dependent cellular cytotoxicity …