Background A trade-off exists between building confidence in health-economic (HE)
decision models and the use of scarce resources. We aimed to create a practical tool …

Economic models which estimate the relative costs and benefits of alternative technologies
are an essential element of the National Institute for Health and Care Excellence's (NICE's) …

For low‐and middle‐income countries (LMICs) to benefit from real‐world evidence
(RWE)/real‐world data (RWD) in both product registration (“regulatory”) decision making …

The neglected tropical diseases (NTDs) thrive mainly among the poorest populations of the
world. The World Health Organization (WHO) has set ambitious targets for eliminating much …

In recent years, the number of mathematical modelling studies has increased steeply. Many
of the questions addressed in these studies are relevant to the development of World Health …

Background A conceptual modeling framework is a methodology that assists modelers
through the process of developing a model structure. Public health interventions tend to …

Healthcare resource allocation decisions are commonly informed by computer model
predictions of population mean costs and health effects. It is common to quantify the …

Aim This study models the cost-effectiveness of brief advice (BA) in primary care for physical
activity (PA) addressing the limitations in the current limited economic literature through the …

BACKGROUND National Institute for Health and Care Excellence (NICE) clinical guidelines
(CGs) make recommendations across large, complex care pathways for broad groups of …

Objectives This article presents a methodological framework for developing health economic
models of whole systems of disease and treatment pathways to inform decisions concerning …