Technology insight: water diffusion MRI—a potential new biomarker of response to cancer therapy

DM Patterson, AR Padhani, DJ Collins - Nature clinical practice …, 2008 - nature.com
Abstract Diffusion-weighted MRI (DW-MRI) is a functional imaging technique that displays
information about the extent and direction of random water motion in tissues. Water …

Musculoskeletal tumors: how to use anatomic, functional, and metabolic MR techniques

LM Fayad, MA Jacobs, X Wang, JA Carrino… - Radiology, 2012 - pubs.rsna.org
Although the function of magnetic resonance (MR) imaging in the evaluation of
musculoskeletal tumors has traditionally been to help identify the extent of disease prior to …

Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy

SE Day, MI Kettunen, FA Gallagher, DE Hu, M Lerche… - Nature medicine, 2007 - nature.com
Measurements of early tumor responses to therapy have been shown, in some cases, to
predict treatment outcome. We show in lymphoma-bearing mice injected intravenously with …

Functional diffusion map: a noninvasive MRI biomarker for early stratification of clinical brain tumor response

BA Moffat, TL Chenevert… - Proceedings of the …, 2005 - National Acad Sciences
Assessment of radiation and chemotherapy efficacy for brain cancer patients is traditionally
accomplished by measuring changes in tumor size several months after therapy has been …

Intravoxel Incoherent Motion Perfusion MR Imaging: A Wake-Up Call1

D Le Bihan - Radiology, 2008 - pubs.rsna.org
Denis Le Bihan, MD, PhD In an article published in this issue of Radiology, Luciani et al (1)
report that perfusion, an important surrogate marker to evaluate the importance of liver …

Diffusion changes precede size reduction in neoadjuvant treatment of breast cancer

MD Pickles, P Gibbs, M Lowry, LW Turnbull - Magnetic resonance imaging, 2006 - Elsevier
Traditionally, tumor response has been assessed via tumor size measurements during the
course of a treatment. However, changes in these morphologically based measures occur …

Differentiation of pancreas carcinoma from healthy pancreatic tissue using multiple b-values: comparison of apparent diffusion coefficient and intravoxel incoherent …

A Lemke, FB Laun, M Klau, TJ Re, D Simon… - Investigative …, 2009 - journals.lww.com
Objectives: To evaluate in detail the diagnostic performance of diffusion-weighted imaging
(DWI) to differentiate pancreas carcinoma from healthy pancreas using the apparent …

Functional diffusion map as an early imaging biomarker for high-grade glioma: correlation with conventional radiologic response and overall survival

DA Hamstra, CJ Galbán, CR Meyer… - Journal of clinical …, 2008 - ascopubs.org
Purpose Assessment of radiologic response (RR) for brain tumors utilizes the Macdonald
criteria 8 to 10 weeks from the start of treatment. Diffusion magnetic resonance imaging …

Time-dependent diffusion MRI in cancer: tissue modeling and applications

O Reynaud - Frontiers in Physics, 2017 - frontiersin.org
In diffusion weighted imaging (DWI), the apparent diffusion coefficient (ADC) has been
recognized as a useful and sensitive surrogate for cell density, paving the way for non …

Detection of head and neck squamous cell carcinoma with diffusion weighted MRI after (chemo) radiotherapy: correlation between radiologic and histopathologic …

V Vandecaveye, F De Keyzer, S Nuyts… - International Journal of …, 2007 - Elsevier
Purpose: To investigate the value of diffusion weighted magnetic resonance imaging (DW-
MRI) in differentiating persistent or recurrent head and neck squamous cell carcinoma …