Lightning Pose: improved animal pose estimation via semi-supervised learning, Bayesian ensembling and cloud-native open-source tools
Contemporary pose estimation methods enable precise measurements of behavior via
supervised deep learning with hand-labeled video frames. Although effective in many cases …
supervised deep learning with hand-labeled video frames. Although effective in many cases …
[HTML][HTML] Integrating across behaviors and timescales to understand the neural control of movement
The nervous system evolved to enable navigation throughout the environment in the pursuit
of resources. Evolutionarily newer structures allowed increasingly complex adaptations but …
of resources. Evolutionarily newer structures allowed increasingly complex adaptations but …
Sensory processing in humans and mice fluctuates between external and internal modes
Perception is known to cycle through periods of enhanced and reduced sensitivity to
external information. Here, we asked whether such slow fluctuations arise as a noise-related …
external information. Here, we asked whether such slow fluctuations arise as a noise-related …
Ultra-high density electrodes improve detection, yield, and cell type identification in neuronal recordings
To understand the neural basis of behavior, it is essential to sensitively and accurately
measure neural activity at single neuron and single spike resolution. Extracellular …
measure neural activity at single neuron and single spike resolution. Extracellular …
Oscillations in an artificial neural network convert competing inputs into a temporal code
The field of computer vision has long drawn inspiration from neuroscientific studies of the
human and non-human primate visual system. The development of convolutional neural …
human and non-human primate visual system. The development of convolutional neural …
Towards a “universal translator” for neural dynamics at single-cell, single-spike resolution
Neuroscience research has made immense progress over the last decade, but our
understanding of the brain remains fragmented and piecemeal: the dream of probing an …
understanding of the brain remains fragmented and piecemeal: the dream of probing an …
Large scale, simultaneous, chronic neural recordings from multiple brain areas
MD Melin, A Khanal, M Vasquez, MB Ryan… - …, 2024 - pmc.ncbi.nlm.nih.gov
Understanding how brain activity is related to animal behavior requires measuring multi-
area interactions on multiple timescales. However, methods to perform chronic …
area interactions on multiple timescales. However, methods to perform chronic …
Pre-existing visual responses in a projection-defined dopamine population explain individual learning trajectories
A Pan-Vazquez, YS Araujo, B McMannon, M Louka… - Current Biology, 2024 - cell.com
A key challenge of learning a new task is that the environment is high dimensional—there
are many different sensory features and possible actions, with typically only a small reward …
are many different sensory features and possible actions, with typically only a small reward …
Changes in the cellular makeup of motor patterning circuits drive courtship song evolution in Drosophila
How evolutionary changes in genes and neurons encode species variation in complex
motor behaviors is largely unknown. Here, we develop genetic tools that permit a neural …
motor behaviors is largely unknown. Here, we develop genetic tools that permit a neural …
An adaptable, reusable, and light implant for chronic Neuropixels probes
Electrophysiology has proven invaluable to record neural activity, and the development of
Neuropixels probes dramatically increased the number of recorded neurons. These probes …
Neuropixels probes dramatically increased the number of recorded neurons. These probes …